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    OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694413, updated on 5-Mar-2024

    Summary

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    Gene symbol
    OBSCN
    Gene description
    obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
    See related
    Ensembl:ENSMMUG00000023096
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See OBSCN in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    115
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (85780477..85949920)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (139205521..139374970)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene gap junction protein gamma 2 Neighboring gene iron-sulfur cluster assembly factor IBA57 Neighboring gene 40S ribosomal protein S10 pseudogene Neighboring gene uncharacterized LOC114669981 Neighboring gene uncharacterized LOC114669986 Neighboring gene tripartite motif containing 11 Neighboring gene tripartite motif containing 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    obscurin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      85780477..85949920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028826438.1 → XP_028682271.1  obscurin isoform X1

      Conserved Domains (11) summary
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8152 → 8230
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6285 → 6464
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4667 → 4743
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6471 → 6595
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:7071 → 7327
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8263 → 8519
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    2. XM_028826436.1 → XP_028682269.1  obscurin isoform X1

      Conserved Domains (11) summary
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8152 → 8230
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6285 → 6464
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4667 → 4743
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6471 → 6595
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:7071 → 7327
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8263 → 8519
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    3. XM_028826450.1 → XP_028682283.1  obscurin isoform X4

      Conserved Domains (11) summary
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8135 → 8213
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6285 → 6464
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:5217 → 5282
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6471 → 6595
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:7054 → 7310
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8246 → 8502
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    4. XM_028826444.1 → XP_028682277.1  obscurin isoform X2

      Conserved Domains (11) summary
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8151 → 8229
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6285 → 6464
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:5217 → 5282
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6471 → 6595
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:7070 → 7326
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8262 → 8518
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    5. XM_028826448.1 → XP_028682281.1  obscurin isoform X3

      Conserved Domains (11) summary
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8151 → 8229
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6285 → 6463
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4667 → 4743
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6470 → 6594
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:7070 → 7326
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8262 → 8518
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    6. XM_028826460.1 → XP_028682293.1  obscurin isoform X9

      Conserved Domains (10) summary
      cd12025
      Location:6101 → 6163
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8063 → 8141
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6196 → 6375
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:5128 → 5193
      IG_like; Immunoglobulin like
      cd00063
      Location:5021 → 5106
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6382 → 6506
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6982 → 7238
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8174 → 8430
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain

    7. XM_028826466.1 → XP_028682299.1  obscurin isoform X10

      Conserved Domains (11) summary
      cd12025
      Location:6099 → 6161
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8061 → 8139
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6194 → 6373
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:5126 → 5191
      IG_like; Immunoglobulin like
      cd00063
      Location:5019 → 5104
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6380 → 6504
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6980 → 7236
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8172 → 8428
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4746 → 4821
      Ig_3; Immunoglobulin domain

    8. XM_028826455.1 → XP_028682288.1  obscurin isoform X6

      Conserved Domains (11) summary
      cd12025
      Location:6102 → 6164
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8064 → 8142
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6197 → 6376
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4579 → 4655
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5022 → 5107
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6383 → 6507
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6983 → 7239
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8175 → 8431
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4749 → 4824
      Ig_3; Immunoglobulin domain

    9. XM_028826498.1 → XP_028682331.1  obscurin isoform X17

      Conserved Domains (11) summary
      cd12025
      Location:6014 → 6076
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7976 → 8054
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6109 → 6288
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:3158 → 3237
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4934 → 5019
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6295 → 6419
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6895 → 7151
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8087 → 8343
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4661 → 4736
      Ig_3; Immunoglobulin domain

    10. XM_028826495.1 → XP_028682328.1  obscurin isoform X16

      Conserved Domains (11) summary
      cd12025
      Location:6014 → 6076
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7976 → 8054
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6109 → 6288
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:5041 → 5106
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4934 → 5019
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6295 → 6419
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6895 → 7151
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8087 → 8343
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4661 → 4736
      Ig_3; Immunoglobulin domain

    11. XM_028826516.1 → XP_028682349.1  obscurin isoform X21

      Conserved Domains (11) summary
      cd12025
      Location:5926 → 5988
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7888 → 7966
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6021 → 6200
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:3158 → 3237
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4846 → 4931
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6207 → 6331
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6807 → 7063
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7999 → 8255
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4573 → 4648
      Ig_3; Immunoglobulin domain

    12. XM_028826535.1 → XP_028682368.1  obscurin isoform X25

      Conserved Domains (11) summary
      cd12025
      Location:5838 → 5900
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7800 → 7878
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5933 → 6112
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4865 → 4930
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4758 → 4843
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6119 → 6243
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6719 → 6975
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7911 → 8167
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4485 → 4560
      Ig_3; Immunoglobulin domain

    13. XM_028826509.1 → XP_028682342.1  obscurin isoform X20

      Conserved Domains (11) summary
      cd12025
      Location:5926 → 5988
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7888 → 7966
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6021 → 6200
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4953 → 5018
      IG_like; Immunoglobulin like
      cd00063
      Location:4846 → 4931
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6207 → 6331
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6807 → 7063
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7999 → 8255
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4573 → 4648
      Ig_3; Immunoglobulin domain

    14. XM_028826531.1 → XP_028682364.1  obscurin isoform X24

      Conserved Domains (11) summary
      cd12025
      Location:5838 → 5900
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7800 → 7878
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5933 → 6112
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4315 → 4391
      IG_like; Immunoglobulin like
      cd00063
      Location:4758 → 4843
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6119 → 6243
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6719 → 6975
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7911 → 8167
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4485 → 4560
      Ig_3; Immunoglobulin domain

    15. XM_028826540.1 → XP_028682373.1  obscurin isoform X26

      Conserved Domains (11) summary
      cd12025
      Location:5750 → 5812
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7712 → 7790
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5845 → 6024
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4227 → 4303
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4670 → 4755
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6031 → 6155
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6631 → 6887
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7823 → 8079
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4397 → 4472
      Ig_3; Immunoglobulin domain

    16. XM_028826547.1 → XP_028682380.1  obscurin isoform X28

      Conserved Domains (11) summary
      cd12025
      Location:5662 → 5724
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7624 → 7702
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5757 → 5936
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4689 → 4754
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4582 → 4667
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5943 → 6067
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6543 → 6799
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7735 → 7991
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4309 → 4384
      Ig_3; Immunoglobulin domain

    17. XM_028826518.1 → XP_028682351.1  obscurin isoform X22

      Conserved Domains (11) summary
      cd12025
      Location:5926 → 5988
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7888 → 7966
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6021 → 6200
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4953 → 5018
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4846 → 4931
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6207 → 6331
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6807 → 7063
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7999 → 8255
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4573 → 4648
      Ig_3; Immunoglobulin domain

    18. XM_028826456.1 → XP_028682289.1  obscurin isoform X7

      Conserved Domains (11) summary
      cd12025
      Location:6102 → 6164
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8064 → 8142
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6197 → 6376
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4579 → 4655
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5022 → 5107
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6383 → 6507
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6983 → 7239
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8175 → 8431
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4749 → 4824
      Ig_3; Immunoglobulin domain

    19. XM_028826543.1 → XP_028682376.1  obscurin isoform X27

      Conserved Domains (11) summary
      cd12025
      Location:5662 → 5724
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7624 → 7702
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5757 → 5936
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4139 → 4215
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4582 → 4667
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5943 → 6067
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6543 → 6799
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7735 → 7991
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4309 → 4384
      Ig_3; Immunoglobulin domain

    20. XM_028826550.1 → XP_028682383.1  obscurin isoform X29

      Conserved Domains (11) summary
      cd12025
      Location:5574 → 5636
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7536 → 7614
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5669 → 5848
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4051 → 4127
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4494 → 4579
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5855 → 5979
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6455 → 6711
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7647 → 7903
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4221 → 4296
      Ig_3; Immunoglobulin domain

    21. XM_028826565.1 → XP_028682398.1  obscurin isoform X31

      Conserved Domains (11) summary
      cd12025
      Location:5486 → 5548
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7448 → 7526
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5581 → 5760
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:3158 → 3237
      IG_like; Immunoglobulin like
      cd00063
      Location:4406 → 4491
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5767 → 5891
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6367 → 6623
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7559 → 7815
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4133 → 4208
      Ig_3; Immunoglobulin domain

    22. XM_028826570.1 → XP_028682403.1  obscurin isoform X32

      Conserved Domains (11) summary
      cd12025
      Location:5398 → 5460
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7360 → 7438
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5493 → 5672
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:3875 → 3951
      IG_like; Immunoglobulin like
      cd00063
      Location:4318 → 4403
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5679 → 5803
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6279 → 6535
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7471 → 7727
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4045 → 4120
      Ig_3; Immunoglobulin domain

    23. XM_028826458.1 → XP_028682291.1  obscurin isoform X8

      Conserved Domains (11) summary
      cd12025
      Location:6102 → 6164
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8064 → 8142
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6197 → 6376
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4579 → 4655
      IG_like; Immunoglobulin like
      cd00063
      Location:5022 → 5107
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6383 → 6507
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6983 → 7239
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8175 → 8431
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4749 → 4824
      Ig_3; Immunoglobulin domain

    24. XM_028826573.1 → XP_028682406.1  obscurin isoform X33

      Conserved Domains (11) summary
      cd12025
      Location:5398 → 5460
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7360 → 7438
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5493 → 5672
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:3158 → 3237
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4318 → 4403
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5679 → 5803
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6279 → 6535
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7471 → 7727
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4045 → 4120
      Ig_3; Immunoglobulin domain

    25. XM_028826579.1 → XP_028682412.1  obscurin isoform X34

      Conserved Domains (11) summary
      cd12025
      Location:5310 → 5372
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7272 → 7350
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5405 → 5584
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4337 → 4402
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4230 → 4315
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5591 → 5715
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6191 → 6447
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7383 → 7639
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:3957 → 4032
      Ig_3; Immunoglobulin domain

    26. XM_028826482.1 → XP_028682315.1  obscurin isoform X12

      Conserved Domains (10) summary
      cd12025
      Location:6098 → 6160
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8060 → 8138
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6193 → 6372
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      cd00063
      Location:5018 → 5103
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6379 → 6503
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6979 → 7235
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8171 → 8427
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4745 → 4820
      Ig_3; Immunoglobulin domain

    27. XM_028826474.1 → XP_028682307.1  obscurin isoform X11

      Conserved Domains (11) summary
      cd12025
      Location:6098 → 6160
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8060 → 8138
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6193 → 6372
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4575 → 4651
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5018 → 5103
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6379 → 6503
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6979 → 7235
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8171 → 8427
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4745 → 4820
      Ig_3; Immunoglobulin domain

    28. XM_028826486.1 → XP_028682319.1  obscurin isoform X13

      Conserved Domains (11) summary
      cd12025
      Location:6098 → 6160
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8060 → 8138
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6193 → 6372
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4575 → 4651
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5018 → 5103
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6379 → 6503
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6979 → 7235
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8171 → 8427
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4745 → 4820
      Ig_3; Immunoglobulin domain

    29. XM_028826502.1 → XP_028682335.1  obscurin isoform X18

      Conserved Domains (10) summary
      cd12025
      Location:6006 → 6068
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7968 → 8046
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6101 → 6280
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      cd00063
      Location:4926 → 5011
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6287 → 6411
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6887 → 7143
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8079 → 8335
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4653 → 4728
      Ig_3; Immunoglobulin domain

    30. XM_028826505.1 → XP_028682338.1  obscurin isoform X19

      Conserved Domains (11) summary
      cd12025
      Location:6006 → 6068
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7968 → 8046
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6101 → 6280
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4483 → 4559
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4926 → 5011
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6287 → 6411
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6887 → 7143
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8079 → 8335
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4653 → 4728
      Ig_3; Immunoglobulin domain

    31. XM_028826524.1 → XP_028682357.1  obscurin isoform X23

      Conserved Domains (11) summary
      cd12025
      Location:5914 → 5976
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7876 → 7954
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6009 → 6188
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:2882 → 2961
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4834 → 4919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6195 → 6319
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6795 → 7051
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7987 → 8243
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4561 → 4636
      Ig_3; Immunoglobulin domain

    32. XM_028826489.1 → XP_028682322.1  obscurin isoform X14

      Conserved Domains (11) summary
      cd12025
      Location:6098 → 6160
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8060 → 8138
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6193 → 6372
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4575 → 4651
      IG_like; Immunoglobulin like
      cd00063
      Location:5018 → 5103
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6379 → 6503
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6979 → 7235
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8171 → 8427
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4745 → 4820
      Ig_3; Immunoglobulin domain

    33. XM_028826453.1 → XP_028682286.1  obscurin isoform X5

      Conserved Domains (11) summary
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8134 → 8212
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6285 → 6464
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:5217 → 5282
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6471 → 6595
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:7053 → 7309
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8245 → 8501
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    34. XM_028826585.1 → XP_028682418.1  obscurin isoform X35

      Conserved Domains (9) summary
      smart00015
      Location:5460 → 5481
      IQ; Calmodulin-binding motif
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00325
      Location:6285 → 6464
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:3158 → 3237
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6471 → 6595
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    35. XM_028826594.1 → XP_028682427.1  obscurin isoform X36

      Conserved Domains (8) summary
      smart00015
      Location:5460 → 5481
      IQ; Calmodulin-binding motif
      cd12025
      Location:6190 → 6252
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00325
      Location:6285 → 6463
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      cd00063
      Location:5110 → 5195
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6470 → 6594
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain
      pfam13927
      Location:4837 → 4912
      Ig_3; Immunoglobulin domain

    36. XM_015114683.2 → XP_014970169.2  obscurin isoform X37

      Conserved Domains (8) summary
      smart00015
      Location:4843 → 4864
      IQ; Calmodulin-binding motif
      cd12025
      Location:5573 → 5635
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00325
      Location:5668 → 5846
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:809 → 883
      IG; Immunoglobulin
      smart00410
      Location:4139 → 4215
      IG_like; Immunoglobulin like
      cd00063
      Location:4493 → 4578
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5853 → 5977
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain

    37. XM_028826492.1 → XP_028682325.1  obscurin isoform X15

      Related
      ENSMMUT00000032486.4
      Conserved Domains (10) summary
      cd12025
      Location:6101 → 6163
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8044 → 8122
      FN3; Fibronectin type 3 domain
      smart00325
      Location:6196 → 6374
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:5128 → 5193
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:5021 → 5106
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6381 → 6505
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6963 → 7219
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:8155 → 8411
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain

    38. XM_028826560.1 → XP_028682393.1  obscurin isoform X30

      Conserved Domains (10) summary
      cd12025
      Location:5573 → 5635
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:7516 → 7594
      FN3; Fibronectin type 3 domain
      smart00325
      Location:5668 → 5846
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      smart00409
      Location:4139 → 4215
      IG; Immunoglobulin
      smart00410
      Location:809 → 883
      IG_like; Immunoglobulin like
      cd00063
      Location:4493 → 4578
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:5853 → 5977
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd14107
      Location:6435 → 6691
      STKc_obscurin_rpt1; Catalytic kinase domain, first repeat, of the Giant Serine/Threonine Kinase Obscurin
      cd14110
      Location:7627 → 7883
      STKc_obscurin_rpt2; Catalytic kinase domain, second repeat, of the Giant Serine/Threonine Kinase Obscurin
      pfam07679
      Location:10 → 99
      I-set; Immunoglobulin I-set domain

    RNA

    1. XR_003719363.1 RNA Sequence

    2. XR_003719369.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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