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    SREBF1 sterol regulatory element binding transcription factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706972, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SREBF1provided by VGNC
    Official Full Name
    sterol regulatory element binding transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:77880
    See related
    Ensembl:ENSMMUG00000023375
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SREBF1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (17639918..17666518, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (17951339..17979375, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106993928 Neighboring gene retinoic acid induced 1 Neighboring gene microRNA mir-33b Neighboring gene uncharacterized LOC114673070 Neighboring gene uncharacterized LOC106993911 Neighboring gene target of myb1 like 2 membrane trafficking protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol regulatory element-binding protein 1
    Names
    sterol regulatory element-binding protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      17639918..17666518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015118741.2 → XP_014974227.1  sterol regulatory element-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      H9EVZ1, H9ZCR8
      Conserved Domains (2) summary
      cd18921
      Location:317 → 391
      bHLHzip_SREBP1; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 1 (SREBP1) and similar proteins
      pfam03154
      Location:87 → 210
      Atrophin-1; Atrophin-1 family

    2. XM_015118744.2 → XP_014974230.1  sterol regulatory element-binding protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A1D5QWQ4, H9EVZ1
      Related
      ENSMMUP00000052484.1, ENSMMUT00000078030.2
      Conserved Domains (3) summary
      pfam05109
      Location:86 → 350
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd18921
      Location:349 → 423
      bHLHzip_SREBP1; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 1 (SREBP1) and similar proteins
      pfam03154
      Location:117 → 240
      Atrophin-1; Atrophin-1 family

    3. XM_015118740.2 → XP_014974226.1  sterol regulatory element-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      F7E4A8, H9EVZ1, I2CU70
      Related
      ENSMMUP00000030771.3, ENSMMUT00000032888.4
      Conserved Domains (3) summary
      pfam05109
      Location:56 → 320
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd18921
      Location:319 → 393
      bHLHzip_SREBP1; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 1 (SREBP1) and similar proteins
      pfam03154
      Location:87 → 210
      Atrophin-1; Atrophin-1 family

    4. XM_028836066.1 → XP_028691899.1  sterol regulatory element-binding protein 1 isoform X5

      UniProtKB/TrEMBL
      F6ZXA5, G7NJ20
      Related
      ENSMMUP00000012722.4, ENSMMUT00000013578.4
      Conserved Domains (3) summary
      pfam05109
      Location:25 → 289
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd18921
      Location:288 → 362
      bHLHzip_SREBP1; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 1 (SREBP1) and similar proteins
      pfam03154
      Location:56 → 179
      Atrophin-1; Atrophin-1 family

    5. XM_015118743.2 → XP_014974229.1  sterol regulatory element-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      G7NJ20
      Conserved Domains (3) summary
      cd00083
      Location:295 → 352
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam15476
      Location:66 → 170
      SAP25; Histone deacetylase complex subunit SAP25
      pfam17040
      Location:102 → 300
      CBP_CCPA; Cellulose-complementing protein A

    6. XM_015118742.2 → XP_014974228.1  sterol regulatory element-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A1D5RJ30, G7NJ20
      Related
      ENSMMUP00000060324.2, ENSMMUT00000070798.2
      Conserved Domains (3) summary
      cd00083
      Location:297 → 354
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam15476
      Location:66 → 170
      SAP25; Histone deacetylase complex subunit SAP25
      pfam17040
      Location:102 → 302
      CBP_CCPA; Cellulose-complementing protein A
    Nucleotide Protein
    Heading Accession and Version

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