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    TOP1MT DNA topoisomerase I mitochondrial [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696782, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TOP1MTprovided by VGNC
    Official Full Name
    DNA topoisomerase I mitochondrialprovided by VGNC
    Primary source
    VGNC:VGNC:79821
    See related
    Ensembl:ENSMMUG00000022933
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TOP1MT in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (143554115..143612077, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (142558031..142581742, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene ZFP41 zinc finger protein Neighboring gene GLI family zinc finger 4 Neighboring gene zinc finger protein 696 Neighboring gene U6 spliceosomal RNA Neighboring gene rhophilin Rho GTPase binding protein 1 Neighboring gene MAF bZIP transcription factor A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA topological change IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrial nucleoid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA topoisomerase I, mitochondrial
    Names
    topoisomerase (DNA) I, mitochondrial
    XP_015001609.2
    XP_028708866.1
    XP_028708867.1
    XP_028708868.1
    XP_028708869.1
    XP_028708870.1
    XP_028708871.1
    XP_028708872.1
    XP_028708873.1
    XP_028708874.1
    XP_028708875.1
    XP_028708876.1
    XP_028708877.1
    XP_028708878.1
    XP_028708879.1
    XP_028708880.1
    XP_028708881.1
    XP_028708882.1
    XP_028708883.1
    XP_028708884.1
    XP_028708885.1
    XP_028708886.1
    XP_028708887.1
    XP_028708888.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      143554115..143612077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028853037.1 → XP_028708870.1  DNA topoisomerase I, mitochondrial isoform X4

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    2. XM_028853053.1 → XP_028708886.1  DNA topoisomerase I, mitochondrial isoform X8

      UniProtKB/TrEMBL
      H9F3N4
      Conserved Domains (2) summary
      smart00435
      Location:114 → 490
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    3. XM_028853048.1 → XP_028708881.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    4. XM_028853043.1 → XP_028708876.1  DNA topoisomerase I, mitochondrial isoform X6

      UniProtKB/TrEMBL
      A0A1D5QET4
      Conserved Domains (2) summary
      smart00435
      Location:165 → 485
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:20 → 234
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    5. XM_028853051.1 → XP_028708884.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    6. XM_028853046.1 → XP_028708879.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    7. XM_028853044.1 → XP_028708877.1  DNA topoisomerase I, mitochondrial isoform X7

      UniProtKB/TrEMBL
      A0A1D5QJV3, F6U741, H9F3N4
      Related
      ENSMMUP00000030204.4, ENSMMUT00000032281.4
      Conserved Domains (2) summary
      smart00435
      Location:165 → 541
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:20 → 234
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    8. XM_028853041.1 → XP_028708874.1  DNA topoisomerase I, mitochondrial isoform X6

      UniProtKB/TrEMBL
      A0A1D5QET4
      Conserved Domains (2) summary
      smart00435
      Location:165 → 485
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:20 → 234
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    9. XM_028853040.1 → XP_028708873.1  DNA topoisomerase I, mitochondrial isoform X6

      UniProtKB/TrEMBL
      A0A1D5QET4
      Conserved Domains (2) summary
      smart00435
      Location:165 → 485
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:20 → 234
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    10. XM_028853047.1 → XP_028708880.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    11. XM_028853042.1 → XP_028708875.1  DNA topoisomerase I, mitochondrial isoform X6

      UniProtKB/TrEMBL
      A0A1D5QET4
      Conserved Domains (2) summary
      smart00435
      Location:165 → 485
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:20 → 234
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    12. XM_028853050.1 → XP_028708883.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    13. XM_028853039.1 → XP_028708872.1  DNA topoisomerase I, mitochondrial isoform X6

      UniProtKB/TrEMBL
      A0A1D5QET4
      Conserved Domains (2) summary
      smart00435
      Location:165 → 485
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:20 → 234
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    14. XM_028853045.1 → XP_028708878.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    15. XM_028853055.1 → XP_028708888.1  DNA topoisomerase I, mitochondrial isoform X9

      Conserved Domains (2) summary
      smart00435
      Location:75 → 395
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:2 → 144
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    16. XM_028853036.1 → XP_028708869.1  DNA topoisomerase I, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A1D5QET4
      Conserved Domains (2) summary
      smart00435
      Location:196 → 516
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:51 → 265
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    17. XM_015146123.2 → XP_015001609.2  DNA topoisomerase I, mitochondrial isoform X3

      UniProtKB/TrEMBL
      H9F3N4
      Related
      ENSMMUP00000070064.1, ENSMMUT00000082375.1
      Conserved Domains (2) summary
      smart00435
      Location:196 → 572
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:51 → 265
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    18. XM_028853054.1 → XP_028708887.1  DNA topoisomerase I, mitochondrial isoform X8

      UniProtKB/TrEMBL
      H9F3N4
      Conserved Domains (2) summary
      smart00435
      Location:114 → 490
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    19. XM_028853052.1 → XP_028708885.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    20. XM_028853049.1 → XP_028708882.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    21. XM_028853038.1 → XP_028708871.1  DNA topoisomerase I, mitochondrial isoform X5

      UniProtKB/TrEMBL
      A0A1D5QET4
      Related
      ENSMMUP00000046553.2, ENSMMUT00000076390.2
      Conserved Domains (2) summary
      smart00435
      Location:114 → 485
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    22. XM_028853034.1 → XP_028708867.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    23. XM_028853033.1 → XP_028708866.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment

    24. XM_028853035.1 → XP_028708868.1  DNA topoisomerase I, mitochondrial isoform X1

      Conserved Domains (2) summary
      smart00435
      Location:114 → 434
      TOPEUc; DNA Topoisomerase I (eukaryota)
      pfam02919
      Location:1 → 183
      Topoisom_I_N; Eukaryotic DNA topoisomerase I, DNA binding fragment
    Nucleotide Protein
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