HNRNPU heterogeneous nuclear ribonucleoprotein U [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: HNRNPUprovided by VGNC
Official Full Name: heterogeneous nuclear ribonucleoprotein Uprovided by VGNC
Primary source: VGNC:VGNC:73500
See related: Ensembl:ENSMMUG00000021098
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	1	NC_041754.1 (4234642..4258320)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	1	NC_027893.1 (221363126..221374603, complement)

Chromosome 1 - NC_041754.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:546820

Hnrnpu (e-PCR), detects polymorphism
- UniSTS:546820

ksks277 (e-PCR)
- UniSTS:514316

HNRPU (e-PCR)
- UniSTS:506402

GDB:6028664 (e-PCR)
- UniSTS:60734

HNRPU_1518 (e-PCR)
- UniSTS:277316

RH18125 (e-PCR)
- UniSTS:42376

RH93803 (e-PCR)
- UniSTS:84362

RH92446 (e-PCR)
- UniSTS:84894

MARC_20677-20678:1024509130:1 (e-PCR)
- UniSTS:268469

D14S1285 (e-PCR)
- UniSTS:10169

A007A33 (e-PCR)
- UniSTS:49593

MARC_26419-26420:1036768776:5 (e-PCR)
- UniSTS:268990

WI-7584 (e-PCR)
- UniSTS:31692

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA polymerase II C-terminal domain binding	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables TFIIH-class transcription factor complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables poly(C) RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables poly(G) binding	IEA Inferred from Electronic Annotation more info	PubMed
enables pre-mRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables promoter-specific chromatin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ribonucleoprotein complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables snRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription corepressor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in CRD-mediated mRNA stabilization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in RNA localization to chromatin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of telomere maintenance via telomerase	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of attachment of mitotic spindle microtubules to kinetochore	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of chromatin organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of mitotic spindle assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of CRD-mediated mRNA stability complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of catalytic step 2 spliceosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in centrosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasmic ribonucleoprotein granule	IEA Inferred from Electronic Annotation more info	PubMed
located_in inactive sex chromosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in kinetochore	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle microtubule	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle midzone	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear chromosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear speck	IEA Inferred from Electronic Annotation more info	PubMed
part_of telomerase holoenzyme complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: heterogeneous nuclear ribonucleoprotein U

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041754.1 Reference Mmul_10 Primary Assembly

Range

4234642..4258320

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_002802090.3 → XP_002802136.2 heterogeneous nuclear ribonucleoprotein U isoform X2

UniProtKB/TrEMBL

H9ETH2

Conserved Domains (3) summary

smart00513
Location:8 → 42

SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

cd12884
Location:269 → 444

SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

pfam13671
Location:480 → 624

AAA_33; AAA domain
XM_001102264.4 → XP_001102264.3 heterogeneous nuclear ribonucleoprotein U isoform X1

UniProtKB/TrEMBL

F6R0Z9, H9ETI5

Related

ENSMMUP00000037521.3, ENSMMUT00000044504.3

Conserved Domains (3) summary

smart00513
Location:8 → 42

SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

cd12884
Location:288 → 463

SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

pfam13671
Location:499 → 643

AAA_33; AAA domain