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    SMPD1 sphingomyelin phosphodiesterase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711248, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMPD1provided by VGNC
    Official Full Name
    sphingomyelin phosphodiesterase 1provided by VGNC
    Primary source
    VGNC:VGNC:77659
    See related
    Ensembl:ENSMMUG00000007717
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SMPD1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (59545857..59550541, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (60386137..60390821, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene hemopexin Neighboring gene amyloid beta precursor protein binding family B member 1 Neighboring gene uncharacterized LOC106993345 Neighboring gene uncharacterized LOC106993347 Neighboring gene V-type proton ATPase subunit E 1 pseudogene Neighboring gene caveolae associated protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acid sphingomyelin phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingomyelin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingomyelin phosphodiesterase
    Names
    sphingomyelin phosphodiesterase 1, acid lysosomal
    XP_001110212.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      59545857..59550541 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001110212.4 → XP_001110212.1  sphingomyelin phosphodiesterase

      See identical proteins and their annotated locations for XP_001110212.1

      UniProtKB/TrEMBL
      F7C9N4, H9ZCN4
      Related
      ENSMMUP00000010133.2, ENSMMUT00000010803.4
      Conserved Domains (3) summary
      smart00741
      Location:87 → 160
      SapB; Saposin (B) Domains
      cd00842
      Location:201 → 496
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
      pfam00149
      Location:254 → 461
      Metallophos; Calcineurin-like phosphoesterase
    Nucleotide Protein
    Heading Accession and Version

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