U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FGA fibrinogen alpha chain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698244, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FGAprovided by VGNC
    Official Full Name
    fibrinogen alpha chainprovided by VGNC
    Primary source
    VGNC:VGNC:100226
    See related
    Ensembl:ENSMMUG00000021303
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FGA in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (152209871..152217631, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (154489004..154495969, complement)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene pleiotropic regulator 1 Neighboring gene fibrinogen beta chain Neighboring gene fibrinogen gamma chain Neighboring gene uncharacterized LOC106998550

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in blood coagulation, common pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fibrinolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of endothelial cell apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in platelet activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in platelet aggregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of heterotypic cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of peptide hormone secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of fibrinogen complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    fibrinogen alpha chain
    Names
    fibrinogen A-alpha-chain

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      152209871..152217631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028848828.1 → XP_028704661.1  fibrinogen alpha chain isoform X2

      UniProtKB/TrEMBL
      F6UZ60
      Conserved Domains (4) summary
      PHA03307
      Location:230 → 436
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00087
      Location:652 → 885
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
      pfam08702
      Location:50 → 187
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam12160
      Location:471 → 531
      Fibrinogen_aC; Fibrinogen alpha C domain

    2. XM_028848827.1 → XP_028704660.1  fibrinogen alpha chain isoform X1

      UniProtKB/TrEMBL
      F6UZ60
      Related
      ENSMMUP00000028061.4, ENSMMUT00000029982.4
      Conserved Domains (4) summary
      PHA03307
      Location:245 → 447
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00087
      Location:665 → 898
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
      pfam08702
      Location:50 → 187
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam12160
      Location:484 → 544
      Fibrinogen_aC; Fibrinogen alpha C domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P68110.1 GenPept UniProtKB/Swiss-Prot:P68110

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.