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    LOC708155 inosine-5'-monophosphate dehydrogenase 1-like [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708155, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC708155
    Gene description
    inosine-5'-monophosphate dehydrogenase 1-like
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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    Genomic context

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    See LOC708155 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (50061343..50064788)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (50127433..50130120)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S8-like Neighboring gene ubiquitin associated protein 1 Neighboring gene ferritin heavy chain pseudogene Neighboring gene DDB1 and CUL4 associated factor 12 Neighboring gene ubiquitin associated protein 2 Neighboring gene oligosaccharyltransferase complex subunit OSTC pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables IMP dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in GTP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: inosine-5'-monophosphate dehydrogenase 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      50061343..50064788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117536.2 → XP_014973022.1  LOW QUALITY PROTEIN: inosine-5'-monophosphate dehydrogenase 1-like

      UniProtKB/TrEMBL
      G7NFM5
      Conserved Domains (4) summary
      COG0517
      Location:143 → 254
      CBS; CBS domain [Signal transduction mechanisms]
      cd00381
      Location:56 → 454
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:142 → 257
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      pfam00478
      Location:56 → 452
      IMPDH; IMP dehydrogenase / GMP reductase domain
    Nucleotide Protein
    Heading Accession and Version

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