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    UBR2 ubiquitin protein ligase E3 component n-recognin 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696507, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UBR2provided by VGNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 2provided by VGNC
    Primary source
    VGNC:VGNC:79318
    See related
    Ensembl:ENSMMUG00000005675
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See UBR2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (126659531..126789858, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (43564575..43694962)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene V-type proton ATPase 16 kDa proteolipid subunit-like Neighboring gene peripherin 2 Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA U13 Neighboring gene transcriptional regulating factor 1 Neighboring gene small nucleolar RNA U3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UBR2
    XP_014991842.2
    XP_014991843.2
    XP_014991844.2
    XP_028703396.1
    XP_028703397.1
    XP_028703398.1
    XP_028703399.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      126659531..126789858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136358.2 → XP_014991844.2  E3 ubiquitin-protein ligase UBR2 isoform X3

      UniProtKB/TrEMBL
      H9FRY1
      Conserved Domains (3) summary
      cd16686
      Location:1107 → 1222
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    2. XM_015136356.2 → XP_014991842.2  E3 ubiquitin-protein ligase UBR2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8ABU8, H9FRY1
      Related
      ENSMMUP00000075350.1, ENSMMUT00000105036.1
      Conserved Domains (3) summary
      cd16686
      Location:1107 → 1222
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    3. XM_015136357.2 → XP_014991843.2  E3 ubiquitin-protein ligase UBR2 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZK35, H9YXX3
      Related
      ENSMMUP00000065543.1, ENSMMUT00000080646.1
      Conserved Domains (3) summary
      cd16686
      Location:1107 → 1222
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    4. XM_028847564.1 → XP_028703397.1  E3 ubiquitin-protein ligase UBR2 isoform X5

      UniProtKB/TrEMBL
      H9FRY1
      Conserved Domains (2) summary
      cd16686
      Location:910 → 1025
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02617
      Location:25 → 103
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    5. XM_028847563.1 → XP_028703396.1  E3 ubiquitin-protein ligase UBR2 isoform X4

      UniProtKB/TrEMBL
      H9FRY1
      Conserved Domains (2) summary
      cd16686
      Location:973 → 1088
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02617
      Location:88 → 166
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    6. XM_028847565.1 → XP_028703398.1  E3 ubiquitin-protein ligase UBR2 isoform X6

      Conserved Domains (3) summary
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS
      cl17238
      Location:1107 → 1179
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    7. XM_028847566.1 → XP_028703399.1  E3 ubiquitin-protein ligase UBR2 isoform X7

      UniProtKB/TrEMBL
      H9F091
      Conserved Domains (2) summary
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    RNA

    1. XR_003728977.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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