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    ADCY8 adenylate cyclase 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695792, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADCY8provided by VGNC
    Official Full Name
    adenylate cyclase 8provided by VGNC
    Primary source
    VGNC:VGNC:69516
    See related
    Ensembl:ENSMMUG00000010440
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADCY8 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (131093099..131357074, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (130125096..130389103, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC114680337 Neighboring gene uncharacterized LOC114680338 Neighboring gene heat shock protein HSP 90-alpha-like Neighboring gene uncharacterized LOC114680340 Neighboring gene uncharacterized LOC114680339

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables adenylate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cAMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylate cyclase type 8
    XP_001084919.1
    XP_015001480.1
    XP_015001481.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      131093099..131357074 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001084919.4 → XP_001084919.1  adenylate cyclase type 8 isoform X1

      See identical proteins and their annotated locations for XP_001084919.1

      UniProtKB/TrEMBL
      A0A1D5Q874, G7N048
      Related
      ENSMMUP00000044242.1, ENSMMUT00000059655.2
      Conserved Domains (3) summary
      pfam00211
      Location:973 → 1172
      Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
      pfam06327
      Location:617 → 711
      DUF1053; Domain of Unknown Function (DUF1053)
      pfam16214
      Location:161 → 400
      AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

    2. XM_015145995.2 → XP_015001481.1  adenylate cyclase type 8 isoform X3

      UniProtKB/TrEMBL
      A0A5F8A0A4, G7N048
      Related
      ENSMMUP00000071345.1, ENSMMUT00000084375.1
      Conserved Domains (4) summary
      smart00044
      Location:366 → 564
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      pfam00211
      Location:907 → 1106
      Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
      pfam06327
      Location:617 → 639
      DUF1053; Domain of Unknown Function (DUF1053)
      pfam16214
      Location:161 → 400
      AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

    3. XM_015145994.2 → XP_015001480.1  adenylate cyclase type 8 isoform X2

      UniProtKB/TrEMBL
      F6YPV1, G7N048
      Related
      ENSMMUP00000031938.2, ENSMMUT00000038857.3
      Conserved Domains (3) summary
      pfam00211
      Location:943 → 1142
      Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
      pfam06327
      Location:617 → 711
      DUF1053; Domain of Unknown Function (DUF1053)
      pfam16214
      Location:161 → 400
      AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    Nucleotide Protein
    Heading Accession and Version

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