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    NPRL2 NPR2 like, GATOR1 complex subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701924, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NPRL2provided by VGNC
    Official Full Name
    NPR2 like, GATOR1 complex subunitprovided by VGNC
    Primary source
    VGNC:VGNC:75251
    Locus tag
    EGK_11602
    See related
    Ensembl:ENSMMUG00000007013
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    TUSC4
    Orthologs
    human mouse all
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    Genomic context

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    See NPRL2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (106476416..106479996, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (91960828..91964406)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 1 Neighboring gene zinc finger MYND-type containing 10 Neighboring gene cytochrome b561 family member D2 Neighboring gene uncharacterized LOC114676352 Neighboring gene transmembrane protein 115 Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to amino acid starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GATOR1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GATOR complex protein NPRL2
    Names
    nitrogen permease regulator 2-like protein
    nitrogen permease regulator-like 2
    tumor suppressor candidate 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      106476416..106479996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001099730.4 → XP_001099730.2  GATOR complex protein NPRL2 isoform X2

      UniProtKB/TrEMBL
      A0A663D7T7, A0A8J8XP93, F7F5X2, G7ML64
      Related
      ENSMMUP00000009211.2, ENSMMUT00000009806.3
      Conserved Domains (1) summary
      cl24021
      Location:7 → 370
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    2. XM_015130850.2 → XP_014986336.1  GATOR complex protein NPRL2 isoform X6

      Conserved Domains (1) summary
      cl24021
      Location:4 → 311
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    3. XM_015130846.2 → XP_014986332.1  GATOR complex protein NPRL2 isoform X6

      Conserved Domains (1) summary
      cl24021
      Location:4 → 311
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    4. XM_015130851.2 → XP_014986337.1  GATOR complex protein NPRL2 isoform X6

      Conserved Domains (1) summary
      cl24021
      Location:4 → 311
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    5. XM_015130843.2 → XP_014986329.1  GATOR complex protein NPRL2 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZGF3
      Conserved Domains (1) summary
      cl24021
      Location:45 → 367
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    6. XM_028844170.1 → XP_028700003.1  GATOR complex protein NPRL2 isoform X5

      UniProtKB/TrEMBL
      A0A5F7ZGF3
      Conserved Domains (1) summary
      cl24021
      Location:45 → 333
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    7. XM_015130842.2 → XP_014986328.1  GATOR complex protein NPRL2 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZGF3
      Related
      ENSMMUP00000064708.1, ENSMMUT00000099774.1
      Conserved Domains (1) summary
      cl24021
      Location:45 → 373
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    8. XM_015130845.2 → XP_014986331.1  GATOR complex protein NPRL2 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZGF3
      Conserved Domains (1) summary
      cl24021
      Location:45 → 343
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    RNA

    1. XR_003727305.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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