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    CAPN9 calpain 9 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719222, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CAPN9provided by VGNC
    Official Full Name
    calpain 9provided by VGNC
    Primary source
    VGNC:VGNC:70537
    See related
    Ensembl:ENSMMUG00000005882
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CAPN9 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (18188330..18241514, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (206965881..207020188)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 13 Neighboring gene small nucleolar RNA U13 Neighboring gene chromosome 1 C1orf198 homolog Neighboring gene angiotensinogen Neighboring gene component of oligomeric golgi complex 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-9
    XP_014981543.1
    XP_028705600.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      18188330..18241514 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126057.2 → XP_014981543.1  calpain-9 isoform X2

      UniProtKB/TrEMBL
      F6TLE9
      Related
      ENSMMUP00000007741.4, ENSMMUT00000008235.4
      Conserved Domains (5) summary
      cd00051
      Location:566 → 621
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00648
      Location:43 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:349 → 491
      Calpain_III; Calpain large subunit, domain III
      pfam13499
      Location:598 → 652
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:600 → 652
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    2. XM_028849767.1 → XP_028705600.1  calpain-9 isoform X1

      Conserved Domains (4) summary
      cd00214
      Location:324 → 473
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:499 → 527
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:49 → 312
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:499 → 531
      EFh_PEF; The penta-EF hand (PEF) family
    Nucleotide Protein
    Heading Accession and Version

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