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    LAMA2 laminin subunit alpha 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715394, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LAMA2provided by VGNC
    Official Full Name
    laminin subunit alpha 2provided by VGNC
    Primary source
    VGNC:VGNC:74225
    See related
    Ensembl:ENSMMUG00000022136
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LAMA2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    68
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (32303885..33078067)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (137979966..138591949, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene elongation factor 1-delta-like Neighboring gene mesoderm-specific transcript homolog protein pseudogene Neighboring gene uncharacterized LOC114677486 Neighboring gene Rho GTPase activating protein 18 Neighboring gene UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit alpha-2
    Names
    laminin, alpha 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      32303885..33078067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028847101.1 → XP_028702934.1  laminin subunit alpha-2 isoform X4

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:1038 → 1082
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1302 → 1435
      LamB; Laminin B domain
      cd00055
      Location:900 → 945
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3012 → 3164
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1789 → 2148
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2108 → 2244
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1664 → 1923
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1131 → 1179
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2864 → 2992
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:14 → 250
      Laminin_N; Laminin N-terminal (Domain VI)

    2. XM_015137478.2 → XP_014992964.2  laminin subunit alpha-2 isoform X7

      UniProtKB/TrEMBL
      F7H3A8, G7MQE4
      Related
      ENSMMUP00000029154.4, ENSMMUT00000031150.4
      Conserved Domains (10) summary
      smart00180
      Location:967 → 1011
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1231 → 1364
      LamB; Laminin B domain
      cd00055
      Location:917 → 965
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:2941 → 3093
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1718 → 2077
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2037 → 2173
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1593 → 1852
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1060 → 1108
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2793 → 2921
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)

    3. XM_015137479.2 → XP_014992965.2  laminin subunit alpha-2 isoform X8

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:967 → 1011
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1231 → 1364
      LamB; Laminin B domain
      cd00055
      Location:917 → 965
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:2937 → 3089
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1718 → 2077
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2037 → 2173
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1593 → 1852
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1060 → 1108
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2789 → 2917
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)

    4. XM_015137474.2 → XP_014992960.2  laminin subunit alpha-2 isoform X2

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:1073 → 1117
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1337 → 1470
      LamB; Laminin B domain
      cd00055
      Location:935 → 980
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3043 → 3195
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1824 → 2183
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2143 → 2279
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1699 → 1958
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1166 → 1214
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2895 → 3023
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)

    5. XM_015137473.2 → XP_014992959.2  laminin subunit alpha-2 isoform X1

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:1073 → 1117
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1337 → 1470
      LamB; Laminin B domain
      cd00055
      Location:935 → 980
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3045 → 3197
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1824 → 2183
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2143 → 2277
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1699 → 1958
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1166 → 1214
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2897 → 3025
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)

    6. XM_015137476.2 → XP_014992962.2  laminin subunit alpha-2 isoform X5

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:1073 → 1117
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1337 → 1470
      LamB; Laminin B domain
      cd00055
      Location:935 → 980
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3001 → 3153
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1778 → 2137
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2097 → 2233
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1653 → 1912
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1166 → 1214
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2853 → 2981
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)

    7. XM_015137477.2 → XP_014992963.2  laminin subunit alpha-2 isoform X6

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:985 → 1029
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1249 → 1382
      LamB; Laminin B domain
      cd00055
      Location:935 → 983
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:2959 → 3111
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1736 → 2095
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2055 → 2191
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1611 → 1870
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1078 → 1126
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2811 → 2939
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)

    8. XM_015137475.2 → XP_014992961.2  laminin subunit alpha-2 isoform X3

      UniProtKB/TrEMBL
      G7MQE4
      Conserved Domains (10) summary
      smart00180
      Location:1055 → 1099
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1319 → 1452
      LamB; Laminin B domain
      cd00055
      Location:917 → 962
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:3029 → 3181
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1806 → 2165
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06009
      Location:2125 → 2261
      Laminin_II; Laminin Domain II
      pfam06008
      Location:1681 → 1940
      Laminin_I; Laminin Domain I
      pfam00053
      Location:1148 → 1196
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:2881 → 3009
      Laminin_G_1; Laminin G domain
      pfam00055
      Location:49 → 285
      Laminin_N; Laminin N-terminal (Domain VI)
    Nucleotide Protein
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