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    GRIN2C glutamate ionotropic receptor NMDA type subunit 2C [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699216, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRIN2Cprovided by VGNC
    Official Full Name
    glutamate ionotropic receptor NMDA type subunit 2Cprovided by VGNC
    Primary source
    VGNC:VGNC:73284
    See related
    Ensembl:ENSMMUG00000005744
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GRIN2C in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (71180127..71199807, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (68518289..68537523, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 9 Neighboring gene transmembrane protein 104 Neighboring gene ferredoxin reductase Neighboring gene fatty acid desaturase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NMDA glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in excitatory postsynaptic potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in long-term synaptic potentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NMDA selective glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor ionotropic, NMDA 2C
    Names
    glutamate [NMDA] receptor subunit epsilon-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      71180127..71199807 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028836768.1 → XP_028692601.1  glutamate receptor ionotropic, NMDA 2C isoform X3

      UniProtKB/TrEMBL
      F6TWJ2, G7NGM8
      Conserved Domains (3) summary
      cd06378
      Location:30 → 389
      PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      cd13718
      Location:400 → 800
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam10565
      Location:837 → 917
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

    2. XM_028836765.1 → XP_028692598.1  glutamate receptor ionotropic, NMDA 2C isoform X3

      UniProtKB/TrEMBL
      F6TWJ2, G7NGM8
      Related
      ENSMMUP00000007584.4, ENSMMUT00000008067.4
      Conserved Domains (3) summary
      cd06378
      Location:30 → 389
      PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      cd13718
      Location:400 → 800
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam10565
      Location:837 → 917
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

    3. XM_028836766.1 → XP_028692599.1  glutamate receptor ionotropic, NMDA 2C isoform X3

      UniProtKB/TrEMBL
      F6TWJ2, G7NGM8
      Conserved Domains (3) summary
      cd06378
      Location:30 → 389
      PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      cd13718
      Location:400 → 800
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam10565
      Location:837 → 917
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

    4. XM_028836764.1 → XP_028692597.1  glutamate receptor ionotropic, NMDA 2C isoform X2

      UniProtKB/TrEMBL
      G7NGM8
      Conserved Domains (3) summary
      cd06378
      Location:105 → 464
      PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      cd13718
      Location:475 → 874
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam10565
      Location:911 → 991
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus

    5. XM_015120278.2 → XP_014975764.2  glutamate receptor ionotropic, NMDA 2C isoform X1

      UniProtKB/TrEMBL
      A0A5F8A2D7, G7NGM8
      Related
      ENSMMUP00000071066.1, ENSMMUT00000099249.1
      Conserved Domains (3) summary
      cd06378
      Location:105 → 464
      PBP1_iGluR_NMDA_NR2; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family
      cd13718
      Location:475 → 875
      PBP2_iGluR_NMDA_Nr2; The ligand-binding domain of the NR2 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      pfam10565
      Location:912 → 992
      NMDAR2_C; N-methyl D-aspartate receptor 2B3 C-terminus
    Nucleotide Protein
    Heading Accession and Version

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