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    ADAM20 ADAM metallopeptidase domain 20 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715827, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAM20provided by VGNC
    Official Full Name
    ADAM metallopeptidase domain 20provided by VGNC
    Primary source
    VGNC:VGNC:107991
    Locus tag
    EGK_18336
    See related
    Ensembl:ENSMMUG00000000202
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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    Genomic context

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    See ADAM20 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (132642411..132671107, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (132791650..132819963, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene disintegrin and metalloproteinase domain-containing protein 20-like Neighboring gene U6 spliceosomal RNA Neighboring gene mediator complex subunit 6 Neighboring gene 60S ribosomal protein L22 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in male gonad development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in sperm head plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disintegrin and metalloproteinase domain-containing protein 20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      132642411..132671107 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144025.2 → XP_014999511.1  disintegrin and metalloproteinase domain-containing protein 20 isoform X1

      UniProtKB/TrEMBL
      F7HHD3
      Conserved Domains (4) summary
      smart00608
      Location:597 → 733
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:318 → 501
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam00200
      Location:521 → 594
      Disintegrin; Disintegrin
      pfam01562
      Location:155 → 263
      Pep_M12B_propep; Reprolysin family propeptide

    2. XM_015144026.2 → XP_014999512.1  disintegrin and metalloproteinase domain-containing protein 20 isoform X2

      UniProtKB/TrEMBL
      F7HHD3, G7MYJ8
      Related
      ENSMMUP00000000284.4, ENSMMUT00000000300.4
      Conserved Domains (4) summary
      smart00608
      Location:542 → 678
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:263 → 446
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam00200
      Location:466 → 539
      Disintegrin; Disintegrin
      pfam01562
      Location:100 → 208
      Pep_M12B_propep; Reprolysin family propeptide
    Nucleotide Protein
    Heading Accession and Version

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