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    NFATC3 nuclear factor of activated T cells 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702390, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NFATC3provided by VGNC
    Official Full Name
    nuclear factor of activated T cells 3provided by VGNC
    Primary source
    VGNC:VGNC:75328
    See related
    Ensembl:ENSMMUG00000021843
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NFATC3 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (55299210..55453563)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (52447243..52601836)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 28 Neighboring gene dihydrouridine synthase 2 Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene small nucleolar RNA SNORA48 Neighboring gene epithelial splicing regulatory protein 2 Neighboring gene phospholipase A2 group XV Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 7 member 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor of activated T-cells, cytoplasmic 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      55299210..55453563
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841546.1 → XP_028697379.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X3

      UniProtKB/TrEMBL
      H9FUW1
      Conserved Domains (2) summary
      cd01178
      Location:569 → 669
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
      cl08275
      Location:421 → 564
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)

    2. XM_028841545.1 → XP_028697378.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X1

      UniProtKB/TrEMBL
      H9FUW1
      Conserved Domains (2) summary
      cd07881
      Location:421 → 594
      RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
      cd01178
      Location:599 → 699
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    3. XM_015126455.2 → XP_014981941.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X4

      UniProtKB/TrEMBL
      F6RNN7, H9FUW1, H9Z9A2
      Related
      ENSMMUP00000032351.2, ENSMMUT00000039265.3
      Conserved Domains (2) summary
      cd07881
      Location:421 → 594
      RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
      cd01178
      Location:599 → 699
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

    4. XM_015126454.2 → XP_014981940.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X2

      UniProtKB/TrEMBL
      F7EIB3, H9FUW1
      Related
      ENSMMUP00000028763.4, ENSMMUT00000030735.4
      Conserved Domains (3) summary
      cd07881
      Location:421 → 594
      RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
      cd01178
      Location:599 → 699
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
      cl41732
      Location:237 → 308
      KLF6_7_N-like; N-terminal domain of Kruppel-like factor (KLF) 6, KLF7, and similar proteins

    RNA

    1. XR_003725626.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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