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    HACD2 3-hydroxyacyl-CoA dehydratase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715374, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HACD2provided by VGNC
    Official Full Name
    3-hydroxyacyl-CoA dehydratase 2provided by VGNC
    Primary source
    VGNC:VGNC:73382
    See related
    Ensembl:ENSMMUG00000002232
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    PTPLB
    Orthologs
    human mouse all
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    Genomic context

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    See HACD2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (152727687..152826545)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (44722531..44816366, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA5 Neighboring gene myosin light chain kinase Neighboring gene uncharacterized LOC114676417 Neighboring gene adenylate cyclase 5 Neighboring gene SEC22 homolog A, vesicle trafficking protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3-hydroxyacyl-CoA dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid elongation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingolipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in very long-chain fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2
    Names
    protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
    NP_001248058.1
    XP_028699222.1
    XP_028699223.1
    XP_028699224.1
    XP_028699225.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261129.1 → NP_001248058.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2

      See identical proteins and their annotated locations for NP_001248058.1

      Status: PROVISIONAL

      Source sequence(s)
      JV044709
      UniProtKB/TrEMBL
      H9F8R2, I0FK04
      Related
      ENSMMUP00000071849.1, ENSMMUT00000085700.1
      Conserved Domains (1) summary
      pfam04387
      Location:85 → 245
      PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      152727687..152826545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843389.1 → XP_028699222.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform X1

      Conserved Domains (1) summary
      pfam04387
      Location:85 → 227
      PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

    2. XM_028843390.1 → XP_028699223.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform X2

      Conserved Domains (1) summary
      pfam04387
      Location:14 → 162
      PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

    3. XM_028843391.1 → XP_028699224.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AD62
      Related
      ENSMMUP00000075811.1, ENSMMUT00000101257.1
      Conserved Domains (1) summary
      pfam04387
      Location:5 → 152
      PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

    4. XM_028843392.1 → XP_028699225.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform X4

      Conserved Domains (1) summary
      pfam04387
      Location:1 → 134
      PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

    RNA

    1. XR_003726946.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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