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    SMC6 structural maintenance of chromosomes 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699570, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMC6provided by VGNC
    Official Full Name
    structural maintenance of chromosomes 6provided by VGNC
    Primary source
    VGNC:VGNC:77746
    See related
    Ensembl:ENSMMUG00000012056
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SMC6 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (91215867..91302275)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (17613311..17701712, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992848 Neighboring gene mesogenin 1 Neighboring gene GEN1 Holliday junction 5' flap endonuclease Neighboring gene visinin like 1 Neighboring gene uncharacterized LOC106992846 Neighboring gene RAD51 associated protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Smc5-Smc6 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    structural maintenance of chromosomes protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      91215867..91302275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015111754.2 → XP_014967240.1  structural maintenance of chromosomes protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q104, F7HFU2
      Related
      ENSMMUP00000070177.1, ENSMMUT00000101954.1
      Conserved Domains (1) summary
      COG1196
      Location:49 → 1070
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_015111757.2 → XP_014967243.1  structural maintenance of chromosomes protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZDL1, G7N9F7
      Related
      ENSMMUP00000063270.1, ENSMMUT00000109292.1
      Conserved Domains (2) summary
      cd03276
      Location:951 → 1049
      ABC_SMC6_euk; ATP-binding cassette domain of eukaryotic SM6 proteins
      cl25732
      Location:49 → 1043
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_015111756.2 → XP_014967242.1  structural maintenance of chromosomes protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q104, F7HFU2
      Related
      ENSMMUP00000041716.1, ENSMMUT00000070431.2
      Conserved Domains (1) summary
      COG1196
      Location:49 → 1070
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_001438932.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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