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    MASP1 MBL associated serine protease 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708206, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MASP1provided by VGNC
    Official Full Name
    MBL associated serine protease 1provided by VGNC
    Primary source
    VGNC:VGNC:74662
    See related
    Ensembl:ENSMMUG00000013004
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MASP1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (10534361..10611502)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (192348382..192423720)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene receptor transporter protein 4 Neighboring gene receptor transporter protein 1 Neighboring gene ribosomal protein L39 like Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in complement activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in zymogen activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in blood microparticle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mannan-binding lectin serine protease 1
    Names
    mannan binding lectin serine peptidase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      10534361..10611502
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843574.1 → XP_028699407.1  mannan-binding lectin serine protease 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QPY1
      Related
      ENSMMUP00000050108.2, ENSMMUT00000071015.2
      Conserved Domains (6) summary
      PHA02639
      Location:269 → 402
      PHA02639; EEV host range protein; Provisional
      smart00020
      Location:418 → 680
      Tryp_SPc; Trypsin-like serine protease
      pfam00084
      Location:270 → 331
      Sushi; Sushi repeat (SCR repeat)
      pfam00431
      Location:154 → 263
      CUB; CUB domain
      pfam14670
      Location:122 → 150
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl00049
      Location:50 → 106
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

    2. XM_015132432.2 → XP_014987918.2  mannan-binding lectin serine protease 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A9D1
      Related
      ENSMMUP00000073571.1, ENSMMUT00000087927.1
      Conserved Domains (6) summary
      cd00033
      Location:301 → 363
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      PHA02639
      Location:300 → 433
      PHA02639; EEV host range protein; Provisional
      cd00041
      Location:28 → 137
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00190
      Location:449 → 694
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam00431
      Location:185 → 294
      CUB; CUB domain
      pfam14670
      Location:153 → 181
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    3. XM_015132435.2 → XP_014987921.1  mannan-binding lectin serine protease 1 isoform X4

      UniProtKB/TrEMBL
      F7HR38, F7HR41, H9FX87
      Related
      ENSMMUP00000017076.4, ENSMMUT00000018241.4
      Conserved Domains (4) summary
      cd00033
      Location:301 → 363
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      cd00041
      Location:28 → 137
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      pfam00431
      Location:185 → 294
      CUB; CUB domain
      pfam14670
      Location:153 → 181
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    4. XM_028843575.1 → XP_028699408.1  mannan-binding lectin serine protease 1 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QPY1
      Related
      ENSMMUP00000017075.3, ENSMMUT00000018240.4
      Conserved Domains (6) summary
      cd00033
      Location:188 → 250
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      PHA02639
      Location:187 → 320
      PHA02639; EEV host range protein; Provisional
      smart00020
      Location:336 → 598
      Tryp_SPc; Trypsin-like serine protease
      pfam00431
      Location:72 → 181
      CUB; CUB domain
      pfam14670
      Location:40 → 68
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl00057
      Location:8 → 67
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
    Heading Accession and Version

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