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    NFE2L2 NFE2 like bZIP transcription factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707606, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NFE2L2provided by VGNC
    Official Full Name
    NFE2 like bZIP transcription factor 2provided by VGNC
    Primary source
    VGNC:VGNC:75332
    See related
    Ensembl:ENSMMUG00000001861
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NFE2L2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (64326140..64382891, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (64272834..64329924, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene keratin, type II cytoskeletal 8 pseudogene Neighboring gene mitochondrial import inner membrane translocase subunit TIM14 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A3 Neighboring gene uncharacterized LOC106992636 Neighboring gene small nucleolar RNA U13 Neighboring gene alkylglycerone phosphate synthase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. Ungvari Z, et al. J Gerontol A Biol Sci Med Sci, 2011 Aug. PMID 21622983, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor erythroid 2-related factor 2
    Names
    nuclear factor (erythroid-derived 2)-like 2
    nuclear factor, erythroid 2 like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257607.1 → NP_001244536.1  nuclear factor erythroid 2-related factor 2

      See identical proteins and their annotated locations for NP_001244536.1

      Status: PROVISIONAL

      Source sequence(s)
      JU334668
      UniProtKB/TrEMBL
      F7GPD8, G7N8E1
      Related
      ENSMMUP00000077481.1, ENSMMUT00000102123.1
      Conserved Domains (2) summary
      cd14720
      Location:495 → 562
      bZIP_NFE2-like; Basic leucine zipper (bZIP) domain of Nuclear Factor, Erythroid-derived 2 (NFE2) and similar proteins: a DNA-binding and dimerization domain
      pfam06886
      Location:41 → 74
      TPX2; Targeting protein for Xklp2 (TPX2)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      64326140..64382891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110369.2 → XP_014965855.2  nuclear factor erythroid 2-related factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QHG6, G7N8E1
      Related
      ENSMMUP00000079084.1, ENSMMUT00000098798.1
      Conserved Domains (2) summary
      cd14720
      Location:479 → 546
      bZIP_NFE2-like; Basic leucine zipper (bZIP) domain of Nuclear Factor, Erythroid-derived 2 (NFE2) and similar proteins: a DNA-binding and dimerization domain
      pfam06886
      Location:25 → 58
      TPX2; Targeting protein for Xklp2 (TPX2)

    2. XM_015110368.2 → XP_014965854.2  nuclear factor erythroid 2-related factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QHG6, G7N8E1
      Related
      ENSMMUP00000061562.1, ENSMMUT00000091446.1
      Conserved Domains (2) summary
      cd14720
      Location:479 → 546
      bZIP_NFE2-like; Basic leucine zipper (bZIP) domain of Nuclear Factor, Erythroid-derived 2 (NFE2) and similar proteins: a DNA-binding and dimerization domain
      pfam06886
      Location:25 → 58
      TPX2; Targeting protein for Xklp2 (TPX2)

    3. XM_028830543.1 → XP_028686376.1  nuclear factor erythroid 2-related factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QHG6, G7N8E1
      Related
      ENSMMUP00000047487.2, ENSMMUT00000064895.2
      Conserved Domains (2) summary
      cd14720
      Location:479 → 546
      bZIP_NFE2-like; Basic leucine zipper (bZIP) domain of Nuclear Factor, Erythroid-derived 2 (NFE2) and similar proteins: a DNA-binding and dimerization domain
      pfam06886
      Location:25 → 58
      TPX2; Targeting protein for Xklp2 (TPX2)
    Nucleotide Protein
    Heading Accession and Version

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