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    ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 722449, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ABL1provided by VGNC
    Official Full Name
    ABL proto-oncogene 1, non-receptor tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:69585
    See related
    Ensembl:ENSMMUG00000012499
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ABL1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (9599097..9784123, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (7776370..7960828, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene fibrinogen C domain containing 1 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene exosome component 2 Neighboring gene PR/SET domain 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase ABL1
    Names
    c-abl oncogene 1, non-receptor tyrosine kinase
    c-abl oncogene 1, receptor tyrosine kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      9599097..9784123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015116552.2 → XP_014972038.2  tyrosine-protein kinase ABL1 isoform X2

      UniProtKB/TrEMBL
      F7EH78, I0FQI2
      Related
      ENSMMUP00000016419.4, ENSMMUT00000017534.4
      Conserved Domains (4) summary
      smart00808
      Location:1006 → 1130
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:123 → 216
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:65 → 118
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:235 → 497
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

    2. XM_015116551.2 → XP_014972037.2  tyrosine-protein kinase ABL1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R032, G7NFJ0, H9YUX8
      Related
      ENSMMUP00000053665.2, ENSMMUT00000068222.2
      Conserved Domains (4) summary
      smart00808
      Location:1025 → 1149
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:142 → 235
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:84 → 137
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:254 → 516
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    Nucleotide Protein
    Heading Accession and Version

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