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    TBK1 TANK binding kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717427, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TBK1provided by VGNC
    Official Full Name
    TANK binding kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:78107
    Locus tag
    EGK_03880
    See related
    Ensembl:ENSMMUG00000007658
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TBK1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (64001821..64050597)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (63205677..63255526)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S11-like Neighboring gene uncharacterized LOC114670882 Neighboring gene uncharacterized LOC114670883 Neighboring gene exportin for tRNA Neighboring gene Ras association domain family member 3 Neighboring gene glucosamine (N-acetyl)-6-sulfatase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1. Diao F, et al. J Virol, 2023 Apr 27. PMID 37039642, Free PMC Article
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase TBK1
    NP_001248122.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261193.1 → NP_001248122.1  serine/threonine-protein kinase TBK1

      See identical proteins and their annotated locations for NP_001248122.1

      Status: PROVISIONAL

      Source sequence(s)
      JU321645
      UniProtKB/TrEMBL
      A0A8J8XXL8, F7DBZ3, G7N7J3
      Related
      ENSMMUP00000010063.2, ENSMMUT00000010727.4
      Conserved Domains (2) summary
      cd12219
      Location:297 → 385
      UBL_TBK1_like; Ubiquitin-Like Domain Of Human Tbk1 and similar proteins
      cd13988
      Location:15 → 330
      STKc_TBK1; Catalytic domain of the Serine/Threonine kinase, TANK Binding Kinase 1

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      64001821..64050597
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials