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    MAP2K4 mitogen-activated protein kinase kinase 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718155, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAP2K4provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase 4provided by VGNC
    Primary source
    VGNC:VGNC:99168
    See related
    Ensembl:ENSMMUG00000019842
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAP2K4 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (11813824..11934654)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (12113179..12233981)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal heavy chain 9 Neighboring gene B-cell CLL/lymphoma 7 protein family member C pseudogene Neighboring gene microRNA mir-762-2 Neighboring gene U11 spliceosomal RNA Neighboring gene small nucleolar RNA U3 Neighboring gene zinc finger protein 18 Neighboring gene dynein light chain Tctex-type 1 pseudogene Neighboring gene uncharacterized LOC106993894 Neighboring gene myocardin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual specificity mitogen-activated protein kinase kinase 4
    XP_001114292.1
    XP_001114330.1
    XP_028691858.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      11813824..11934654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001114292.4 → XP_001114292.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X1

      See identical proteins and their annotated locations for XP_001114292.1

      UniProtKB/TrEMBL
      A0A1D5QAU9, H9FBU8
      Related
      ENSMMUP00000045167.1, ENSMMUT00000078314.2
      Conserved Domains (1) summary
      cd06616
      Location:106 → 396
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

    2. XM_001114330.4 → XP_001114330.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X2

      See identical proteins and their annotated locations for XP_001114330.1

      UniProtKB/TrEMBL
      F7FU91, H9FBU8
      Related
      ENSMMUP00000026088.4, ENSMMUT00000027885.4
      Conserved Domains (1) summary
      cd06616
      Location:95 → 385
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

    3. XM_028836025.1 → XP_028691858.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X3

      UniProtKB/TrEMBL
      H9FBU8
      Conserved Domains (1) summary
      cd06616
      Location:106 → 357
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4
    Nucleotide Protein
    Heading Accession and Version

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