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    CD274 CD274 molecule [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716043, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CD274provided by VGNC
    Official Full Name
    CD274 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:70814
    Locus tag
    EGK_07725
    See related
    Ensembl:ENSMMUG00000012235
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CD274 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (78309994..78330073, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (78974909..78995400, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene RIC1 homolog, RAB6A GEF complex partner 1 Neighboring gene programmed cell death 1 ligand 2 Neighboring gene uncharacterized LOC114672797 Neighboring gene uncharacterized LOC114672798 Neighboring gene E3 ubiquitin-protein ligase RNF152-like Neighboring gene plasminogen receptor with a C-terminal lysine

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in T cell costimulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    programmed cell death 1 ligand 1
    Names
    programmed cell death ligand 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083889.1 → NP_001077358.1  programmed cell death 1 ligand 1 precursor

      See identical proteins and their annotated locations for NP_001077358.1

      Status: PROVISIONAL

      Source sequence(s)
      EF444814
      UniProtKB/TrEMBL
      A4GW29, A4GW31
      Related
      ENSMMUP00000039207.2, ENSMMUT00000046162.3
      Conserved Domains (2) summary
      smart00410
      Location:24 → 130
      IG_like; Immunoglobulin like
      cl11960
      Location:66 → 114
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      78309994..78330073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015117668.2 → XP_014973154.1  programmed cell death 1 ligand 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F8A285, A0A8J8Y3P9, A4GW31, F6VEW6
      Related
      ENSMMUP00000071043.1, ENSMMUT00000101160.1
      Conserved Domains (2) summary
      smart00410
      Location:24 → 130
      IG_like; Immunoglobulin like
      cl11960
      Location:66 → 114
      Ig; Immunoglobulin domain

    2. XM_015117665.2 → XP_014973151.1  programmed cell death 1 ligand 1 isoform X2

      UniProtKB/TrEMBL
      A4GW31
      Conserved Domains (2) summary
      smart00410
      Location:24 → 130
      IG_like; Immunoglobulin like
      cl11960
      Location:66 → 114
      Ig; Immunoglobulin domain

    3. XM_028834391.1 → XP_028690224.1  programmed cell death 1 ligand 1 isoform X1

      UniProtKB/TrEMBL
      A4GW31
      Conserved Domains (1) summary
      cl11960
      Location:54 → 117
      Ig; Immunoglobulin domain

    4. XM_028834392.1 → XP_028690225.1  programmed cell death 1 ligand 1 isoform X1

      UniProtKB/TrEMBL
      A4GW31
      Conserved Domains (1) summary
      cl11960
      Location:54 → 117
      Ig; Immunoglobulin domain

    RNA

    1. XR_003723007.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials