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    GSTT1 glutathione S-transferase theta 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700314, updated on 5-Mar-2024

    Summary

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    Gene symbol
    GSTT1
    Gene description
    glutathione S-transferase theta 1
    See related
    Ensembl:ENSMMUG00000053799
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GSTT1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (28154874..28164799, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (65947600..65957544, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene ral-GDS-related protein Neighboring gene glutathione S-transferase theta-3-like Neighboring gene glutathione S-transferase theta 2B Neighboring gene glutathione S-transferase theta 4 Neighboring gene calcineurin binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic identification and characterization of glutathione S-transferases in cynomolgus macaque. Uno Y, et al. Biochem Pharmacol, 2013 Sep 1. PMID 23827461
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione S-transferase theta-1
    Names
    glutathione S-transferase T1
    NP_001305110.1
    XP_015005357.2
    XP_015005358.1
    XP_015005359.2
    XP_028683062.1
    XP_028683063.1
    XP_028683064.1
    XP_028683065.1
    XP_028683066.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001318181.1 → NP_001305110.1  glutathione S-transferase theta-1

      Status: PROVISIONAL

      Source sequence(s)
      KC734510
      UniProtKB/TrEMBL
      A0A023JCR6, A0A5F7ZJM7, H9EVB1
      Related
      ENSMMUP00000064824.1, ENSMMUT00000098325.1
      Conserved Domains (3) summary
      cd03183
      Location:93 → 216
      GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases
      COG0625
      Location:3 → 212
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03050
      Location:3 → 78
      GST_N_Theta; GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      28154874..28164799 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827229.1 → XP_028683062.1  glutathione S-transferase theta-1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZJM7
      Conserved Domains (2) summary
      cd03183
      Location:140 → 265
      GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases
      cd03050
      Location:3 → 127
      GST_N_Theta; GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with ...

    2. XM_015149873.2 → XP_015005359.2  glutathione S-transferase theta-1 isoform X6

      Conserved Domains (2) summary
      cd03183
      Location:103 → 202
      GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases
      cl00388
      Location:3 → 37
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    3. XM_028827233.1 → XP_028683066.1  glutathione S-transferase theta-1 isoform X5

      Conserved Domains (1) summary
      cl02776
      Location:1 → 98
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

    4. XM_015149872.2 → XP_015005358.1  glutathione S-transferase theta-1 isoform X5

      Conserved Domains (1) summary
      cl02776
      Location:1 → 98
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

    5. XM_028827232.1 → XP_028683065.1  glutathione S-transferase theta-1 isoform X5

      Conserved Domains (1) summary
      cl02776
      Location:1 → 98
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

    6. XM_028827231.1 → XP_028683064.1  glutathione S-transferase theta-1 isoform X3

      Conserved Domains (1) summary
      cl02776
      Location:47 → 146
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

    7. XM_028827230.1 → XP_028683063.1  glutathione S-transferase theta-1 isoform X2

      Conserved Domains (1) summary
      cd03183
      Location:51 → 176
      GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases

    8. XM_015149871.2 → XP_015005357.2  glutathione S-transferase theta-1 isoform X4

      Conserved Domains (1) summary
      cd03183
      Location:17 → 142
      GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases
    Nucleotide Protein
    Heading Accession and Version

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