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    XBP1 X-box binding protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713863, updated on 17-Aug-2024

    Summary

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    Official Symbol
    XBP1provided by VGNC
    Official Full Name
    X-box binding protein 1provided by VGNC
    Primary source
    VGNC:VGNC:78806
    See related
    Ensembl:ENSMMUG00000007215
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    XBP1P1
    Orthologs
    human mouse all
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    Genomic context

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    See XBP1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (22747004..22754139)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (70649465..70656612, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene zinc and ring finger 3 Neighboring gene axonemal dynein light intermediate polypeptide 1-like Neighboring gene coiled-coil domain containing 117 Neighboring gene HscB mitochondrial iron-sulfur cluster cochaperone Neighboring gene checkpoint kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    X-box-binding protein 1
    Names
    X-box binding protein 1 pseudogene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190861.2 → NP_001177790.1  X-box-binding protein 1 isoform XBP1(U)

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform, XBP1(U).
      Source sequence(s)
      CO647703, JU336259
      UniProtKB/TrEMBL
      H9FZF4
      Conserved Domains (1) summary
      cd14691
      Location:70 → 126
      bZIP_XBP1; Basic leucine zipper (bZIP) domain of X-box binding protein 1 (XBP1) and similar proteins: a DNA-binding and dimerization domain

    2. NM_001271739.1 → NP_001258668.1  X-box-binding protein 1 isoform XBP1(S)

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks a 26 nt segment in the CDS compared to variant 1, that causes a frameshift. The resulting isoform, XBP1(S), has the same N-terminus, but a longer and distinct C-terminus compared to isoform XBP1(U). Isoform XBP1(S) functions as a transcription factor.
      Source sequence(s)
      CO647703, JU336259
      UniProtKB/TrEMBL
      F7EKN6, H9FZF3
      Related
      ENSMMUP00000009461.4, ENSMMUT00000010080.4
      Conserved Domains (1) summary
      cd14691
      Location:70 → 126
      bZIP_XBP1; Basic leucine zipper (bZIP) domain of X-box binding protein 1 (XBP1) and similar proteins: a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      22747004..22754139
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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