KISS1 KiSS-1 metastasis suppressor [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: KISS1provided by VGNC
Official Full Name: KiSS-1 metastasis suppressorprovided by VGNC
Primary source: VGNC:VGNC:74024
See related: Ensembl:ENSMMUG00000003647
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	1	NC_041754.1 (61696349..61703347, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	1	NC_027893.1 (162433718..162440680)

Chromosome 1 - NC_041754.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Inverse age-related changes between hypothalamic NPY and KISS1 gene expression during pubertal initiation in male rhesus monkey.
Title: Inverse age-related changes between hypothalamic NPY and KISS1 gene expression during pubertal initiation in male rhesus monkey.
While collaborative kisspeptin and NKB signaling to GnRH neurons was active before puberty onset, after initiation of puberty the role of NKB signaling in GnRH neurons diminished and kisspeptin signaling assumed the primary stimulatory role in the regulation of GnRH release in male monkeys.
Title: Role of Kisspeptin and Neurokinin B Signaling in Male Rhesus Monkey Puberty.
Kisspeptin receptor was detected in Sertoli cells in the periphery of the seminiferous tubules in adult testes of both rhesus monkey and common marmoset. In contrast, kisspeptin was not localized in the seminiferous epithelium and was detected only in the interstitial compartment of the adult rhesus monkey testis.
Title: Immunocytochemical localization of kisspeptin and kisspeptin receptor in the primate testis.
findings support the view that, in primates, as in rodents and sheep, kisspeptin signalling in ARC neurones appears to play an important role in mediating the negative-feedback action of E on gonadotrophin secretion
Title: Ovarian regulation of kisspeptin neurones in the arcuate nucleus of the rhesus monkey (macaca mulatta).
Hypothalamic KISS1 and KISS1R decrease after a short-term fasting.
Title: Decrease in hypothalamic Kiss1 and Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta).
Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence.
Title: Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence of female rhesus macaques.
morphological findings obtained in the present study are consistent with the notion that kisspeptin may act directly at the level of the pituitary
Title: Studies of the localisation of kisspeptin within the pituitary of the rhesus monkey (Macaca mulatta) and the effect of kisspeptin on the release of non-gonadotropic pituitary hormones.
Results suggest that the neurobiology of the negative feedback action of testicular testosterone on LH secretion in the monkey may be mediated by kisspeptinergic neurones upstream to the GnRH network.
Title: Evidence that down regulation of hypothalamic KiSS-1 expression is involved in the negative feedback action of testosterone to regulate luteinising hormone secretion in the adult male rhesus monkey (Macaca mulatta).

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General gene information

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Markers

STS-T52659 (e-PCR)
- UniSTS:8556

G62032 (e-PCR)
- UniSTS:139122

SHGC-76112 (e-PCR)
- UniSTS:9446

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables kisspeptin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed