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    PTRH2 peptidyl-tRNA hydrolase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711736, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PTRH2provided by VGNC
    Official Full Name
    peptidyl-tRNA hydrolase 2provided by VGNC
    Primary source
    VGNC:VGNC:76526
    Locus tag
    EGK_08597
    See related
    Ensembl:ENSMMUG00000001572
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PTRH2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (37096715..37107297)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (53190048..53200643, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene microRNA mir-21 Neighboring gene vacuole membrane protein 1 Neighboring gene clathrin heavy chain Neighboring gene DEAH-box helicase 40

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aminoacyl-tRNA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of anoikis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of anoikis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peptidyl-tRNA hydrolase 2, mitochondrial
    NP_001181368.1
    XP_014975460.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194439.1 → NP_001181368.1  peptidyl-tRNA hydrolase 2, mitochondrial

      See identical proteins and their annotated locations for NP_001181368.1

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000162
      UniProtKB/TrEMBL
      A0A8J8Y7Y0, F7GV88, G7NHZ0, H9F7N6
      Related
      ENSMMUP00000002102.2, ENSMMUT00000002225.4
      Conserved Domains (1) summary
      cd02430
      Location:65 → 179
      PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      37096715..37107297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015119974.2 → XP_014975460.1  peptidyl-tRNA hydrolase 2, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8J8Y7Y0, F7GV88, G7NHZ0, H9F7N6
      Conserved Domains (1) summary
      cd02430
      Location:65 → 179
      PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...
    Nucleotide Protein
    Heading Accession and Version

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