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    ITGA1 integrin subunit alpha 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703456, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITGA1provided by VGNC
    Official Full Name
    integrin subunit alpha 1provided by VGNC
    Primary source
    VGNC:VGNC:73772
    See related
    Ensembl:ENSMMUG00000001753
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITGA1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (51072315..51242993)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (53685824..53857753)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene mortality factor 4-like protein 2 Neighboring gene uncharacterized LOC114678785 Neighboring gene pelota mRNA surveillance and ribosome rescue factor Neighboring gene uncharacterized LOC106998766 Neighboring gene integrin subunit alpha 2 Neighboring gene molybdenum cofactor synthesis 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-1
    Names
    integrin, alpha 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      51072315..51242993
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001094788.4 → XP_001094788.1  integrin alpha-1

      See identical proteins and their annotated locations for XP_001094788.1

      UniProtKB/TrEMBL
      F7GLS1
      Related
      ENSMMUP00000002340.4, ENSMMUT00000002475.4
      Conserved Domains (3) summary
      smart00191
      Location:568 → 621
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:171 → 351
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam08441
      Location:664 → 1051
      Integrin_alpha2; Integrin alpha
    Nucleotide Protein
    Heading Accession and Version

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