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    WWOX WW domain containing oxidoreductase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715635, updated on 17-Aug-2024

    Summary

    Official Symbol
    WWOXprovided by VGNC
    Official Full Name
    WW domain containing oxidoreductaseprovided by VGNC
    Primary source
    VGNC:VGNC:78805
    See related
    Ensembl:ENSMMUG00000010610
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See WWOX in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (65141618..66265691)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (62599305..63769516)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene keratin, type II cytoskeletal 8 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene U6 snRNA-associated Sm-like protein LSm3 pseudogene Neighboring gene uncharacterized LOC106995086 Neighboring gene 40S ribosomal protein S3-like Neighboring gene uncharacterized LOC114674417 Neighboring gene uncharacterized LOC114674418 Neighboring gene uncharacterized LOC114674325 Neighboring gene MAF bZIP transcription factor

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    WW domain-containing oxidoreductase
    XP_001105944.3
    XP_028696945.1
    XP_028696946.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      65141618..66265691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001105944.4XP_001105944.3  WW domain-containing oxidoreductase isoform X1

      UniProtKB/TrEMBL
      F6S5M5, H9EVT4
      Related
      ENSMMUP00000032305.3, ENSMMUT00000039219.3
      Conserved Domains (3) summary
      cd09809
      Location:124407
      human_WWOX_like_SDR_c-like; human WWOX (WW domain-containing oxidoreductase)-like, classical (c)-like SDRs
      cd00201
      Location:6090
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:1847
      WW; WW domain
    2. XM_028841112.1XP_028696945.1  WW domain-containing oxidoreductase isoform X2

      UniProtKB/TrEMBL
      G7NR44
      Conserved Domains (2) summary
      cd00201
      Location:1947
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cl25409
      Location:124352
      SDR; Short-chain dehydrogenases/reductases (SDR)
    3. XM_028841113.1XP_028696946.1  WW domain-containing oxidoreductase isoform X3

      Conserved Domains (2) summary
      cd00201
      Location:1947
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cl25409
      Location:124264
      SDR; Short-chain dehydrogenases/reductases (SDR)