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    KMT2C lysine methyltransferase 2C [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716753, updated on 17-Aug-2024

    Summary

    Official Symbol
    KMT2Cprovided by VGNC
    Official Full Name
    lysine methyltransferase 2Cprovided by VGNC
    Primary source
    VGNC:VGNC:74043
    See related
    Ensembl:ENSMMUG00000007212
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    MLL3
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See KMT2C in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    67
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (178118161..178416058, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (178342486..178569267, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene small nucleolar RNA U13 Neighboring gene 40S ribosomal protein S24 pseudogene Neighboring gene septin-7-like Neighboring gene uncharacterized LOC106997727 Neighboring gene collagen alpha-2(I) chain-like Neighboring gene chaperonin containing TCP1 subunit 8 like 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of MLL3/4 complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    histone-lysine N-methyltransferase 2C
    Names
    myeloid/lymphoid or mixed-lineage leukemia 3
    XP_014990827.2
    XP_014990828.2
    XP_028702330.1
    XP_028702331.1
    XP_028702332.1
    XP_028702333.1
    XP_028702334.1
    XP_028702335.1
    XP_028702336.1
    XP_028702337.1
    XP_028702338.1
    XP_028702339.1
    XP_028702340.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      178118161..178416058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846498.1XP_028702331.1  histone-lysine N-methyltransferase 2C isoform X1

      UniProtKB/TrEMBL
      F7EK45
      Conserved Domains (19) summary
      smart00317
      Location:48454966
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49684984
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18322367
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44754579
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31943276
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36373813
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22882696
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46244675
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46814765
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:17071790
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16691720
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    2. XM_028846507.1XP_028702340.1  histone-lysine N-methyltransferase 2C isoform X12

      UniProtKB/TrEMBL
      F7EK45
      Conserved Domains (19) summary
      smart00317
      Location:48254946
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49484964
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18162351
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44594563
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31783260
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36213797
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22722680
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46084659
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46654749
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:16911774
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16531704
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    3. XM_028846502.1XP_028702335.1  histone-lysine N-methyltransferase 2C isoform X5

      UniProtKB/TrEMBL
      F7EK45
      Conserved Domains (19) summary
      smart00317
      Location:48344955
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49574973
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18212356
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10741096
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:9991045
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:942998
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10761126
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44644568
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31833265
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36263802
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22772685
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46134664
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46704754
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:16961779
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16581709
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    4. XM_028846499.1XP_028702332.1  histone-lysine N-methyltransferase 2C isoform X2

      UniProtKB/TrEMBL
      F7EK45
      Conserved Domains (19) summary
      smart00317
      Location:48444965
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49674983
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18322367
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44744578
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31943276
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36373813
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22882696
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46234674
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46804764
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:17071790
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16691720
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    5. XM_028846497.1XP_028702330.1  histone-lysine N-methyltransferase 2C isoform X1

      UniProtKB/TrEMBL
      F7EK45
      Related
      ENSMMUP00000009471.4, ENSMMUT00000010090.4
      Conserved Domains (19) summary
      smart00317
      Location:48454966
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49684984
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18322367
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44754579
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31943276
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36373813
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22882696
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46244675
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46814765
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:17071790
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16691720
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    6. XM_028846504.1XP_028702337.1  histone-lysine N-methyltransferase 2C isoform X7

      UniProtKB/TrEMBL
      F7EK45
      Conserved Domains (19) summary
      smart00317
      Location:47774898
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49004916
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:17642299
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10171039
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:276321
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:399450
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:942988
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:323368
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:885941
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10191069
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:180263
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44074511
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam11489
      Location:35693745
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22202628
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:45564607
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46134697
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:16391722
      Tma16; Translation machinery-associated protein 16
      pfam12474
      Location:31233209
      PKK; Polo kinase kinase
      cl00082
      Location:16011652
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    7. XM_028846506.1XP_028702339.1  histone-lysine N-methyltransferase 2C isoform X9

      UniProtKB/TrEMBL
      F7EKH5
      Conserved Domains (19) summary
      smart00317
      Location:46614782
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:47844800
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:16482183
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:901923
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:160205
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:283334
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:826872
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:207252
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:769825
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:903953
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:64147
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:42914395
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam11489
      Location:34533629
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:21042512
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:44404491
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:44974581
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:15231606
      Tma16; Translation machinery-associated protein 16
      pfam12474
      Location:30073093
      PKK; Polo kinase kinase
      cl00082
      Location:14851536
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    8. XM_015135341.2XP_014990827.2  histone-lysine N-methyltransferase 2C isoform X10

      UniProtKB/TrEMBL
      F7EKH5
      Related
      ENSMMUP00000009468.4, ENSMMUT00000010087.4
      Conserved Domains (19) summary
      smart00317
      Location:46574778
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:47804796
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:16442179
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:897919
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:156201
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:279330
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:822868
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:203248
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:765821
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:899949
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:60143
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:42874391
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam11489
      Location:34493625
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:21002508
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:44364487
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:44934577
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:15191602
      Tma16; Translation machinery-associated protein 16
      pfam12474
      Location:30033089
      PKK; Polo kinase kinase
      cl00082
      Location:14811532
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    9. XM_015135342.2XP_014990828.2  histone-lysine N-methyltransferase 2C isoform X11

      UniProtKB/TrEMBL
      F7EKH5
      Conserved Domains (19) summary
      smart00317
      Location:45404661
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:46634679
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:15272062
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:780802
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:3984
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:162213
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:705751
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:86131
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:648704
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:782832
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:41704274
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam11489
      Location:33323508
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:19832391
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:43194370
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:43764460
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:14021485
      Tma16; Translation machinery-associated protein 16
      pfam12474
      Location:28862972
      PKK; Polo kinase kinase
      cl00082
      Location:13641415
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:126
      PHD_SF; PHD finger superfamily
    10. XM_028846501.1XP_028702334.1  histone-lysine N-methyltransferase 2C isoform X4

      UniProtKB/TrEMBL
      F7EK45
      Conserved Domains (19) summary
      smart00317
      Location:48414962
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49644980
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18322367
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44754579
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31943276
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36373813
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22882696
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46244675
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46814765
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:17071790
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16691720
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    11. XM_028846503.1XP_028702336.1  histone-lysine N-methyltransferase 2C isoform X6

      UniProtKB/TrEMBL
      F7EK45
      Related
      ENSMMUP00000075414.1, ENSMMUT00000103064.1
      Conserved Domains (19) summary
      smart00317
      Location:47904911
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49134929
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18322367
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44204524
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31943276
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36373813
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22882696
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:45694620
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46264710
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:17071790
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16691720
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    12. XM_028846500.1XP_028702333.1  histone-lysine N-methyltransferase 2C isoform X3

      UniProtKB/TrEMBL
      F7EK45
      Related
      ENSMMUP00000009467.4, ENSMMUT00000010086.4
      Conserved Domains (19) summary
      smart00317
      Location:48444965
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49674983
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18322367
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44744578
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31943276
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36373813
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22882696
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46234674
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46804764
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:17071790
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16691720
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    13. XM_028846505.1XP_028702338.1  histone-lysine N-methyltransferase 2C isoform X8

      UniProtKB/TrEMBL
      F7EK45
      Related
      ENSMMUP00000072254.1, ENSMMUT00000096978.1
      Conserved Domains (19) summary
      smart00317
      Location:47744895
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48974913
      PostSET; Cysteine-rich motif following a subset of SET domains
      PHA03247
      Location:18162351
      PHA03247; large tegument protein UL36; Provisional
      sd00025
      Location:10851107
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:344389
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:467518
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10101056
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:391436
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9531009
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10871137
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:248331
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44044508
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:31783260
      Myosin_tail_1; Myosin tail
      pfam11489
      Location:36213797
      Aim21; Altered inheritance of mitochondria protein 21
      pfam03154
      Location:22722680
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:45534604
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46104694
      FYRC; F/Y rich C-terminus
      pfam11176
      Location:16911774
      Tma16; Translation machinery-associated protein 16
      cl00082
      Location:16531704
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...