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    PPP4R3B protein phosphatase 4 regulatory subunit 3B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718961, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PPP4R3Bprovided by VGNC
    Official Full Name
    protein phosphatase 4 regulatory subunit 3Bprovided by VGNC
    Primary source
    VGNC:VGNC:76342
    See related
    Ensembl:ENSMMUG00000007001
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    SMEK2; KIAA1387
    Orthologs
    human mouse all
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    Genomic context

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    See PPP4R3B in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (53030448..53103487)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (56526727..56598000, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene EGF containing fibulin extracellular matrix protein 1 Neighboring gene polyribonucleotide nucleotidyltransferase 1 Neighboring gene small nucleolar RNA SNORA12 Neighboring gene cilia and flagella associated protein 36 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein phosphatase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of protein phosphatase 4 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 4 regulatory subunit 3B
    Names
    SMEK homolog 2, suppressor of mek1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      53030448..53103487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015112397.2 → XP_014967883.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X6

      UniProtKB/TrEMBL
      F7DKA4, H9ZBK2
      Conserved Domains (2) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    2. XM_015112392.2 → XP_014967878.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1

      UniProtKB/TrEMBL
      H9FXJ5, H9ZBK0
      Conserved Domains (2) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    3. XM_015112398.2 → XP_014967884.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X8

      UniProtKB/TrEMBL
      A0A5K1VAC1
      Related
      ENSMMUP00000071707.1, ENSMMUT00000102486.1
      Conserved Domains (2) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    4. XM_015112396.2 → XP_014967882.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X5

      UniProtKB/TrEMBL
      A0A5K1V8W7, F7DKA4, H9ZBK2
      Related
      ENSMMUP00000062490.1, ENSMMUT00000108218.1
      Conserved Domains (3) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      pfam08365
      Location:624 → 661
      IGF2_C; Insulin-like growth factor II E-peptide
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    5. XM_015112393.2 → XP_014967879.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X2

      UniProtKB/TrEMBL
      H9FXJ5
      Conserved Domains (3) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      pfam08365
      Location:663 → 700
      IGF2_C; Insulin-like growth factor II E-peptide
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    6. XM_015112395.2 → XP_014967881.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X4

      UniProtKB/TrEMBL
      A0A5F8A476
      Conserved Domains (3) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      pfam08365
      Location:631 → 668
      IGF2_C; Insulin-like growth factor II E-peptide
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    7. XM_002799228.3 → XP_002799274.2  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X7

      UniProtKB/TrEMBL
      A0A5K1VAC1, H9ETV2
      Related
      ENSMMUP00000009187.4, ENSMMUT00000009782.4
      Conserved Domains (3) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      pfam08365
      Location:592 → 629
      IGF2_C; Insulin-like growth factor II E-peptide
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    8. XM_002799229.3 → XP_002799275.2  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X3

      UniProtKB/TrEMBL
      F6VU24, H9FXJ5, H9FXJ6
      Related
      ENSMMUP00000073295.1, ENSMMUT00000088883.1
      Conserved Domains (3) summary
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      pfam08365
      Location:645 → 682
      IGF2_C; Insulin-like growth factor II E-peptide
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    9. XM_028831653.1 → XP_028687486.1  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X9

      UniProtKB/TrEMBL
      F7DKB5, H9ETK8, H9FXJ5
      Conserved Domains (3) summary
      pfam08365
      Location:677 → 714
      IGF2_C; Insulin-like growth factor II E-peptide
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain

    10. XM_001112386.4 → XP_001112386.3  serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X9

      UniProtKB/TrEMBL
      F7DKB5, H9ETK8, H9FXJ5
      Related
      ENSMMUP00000076306.1, ENSMMUT00000086960.1
      Conserved Domains (3) summary
      pfam08365
      Location:677 → 714
      IGF2_C; Insulin-like growth factor II E-peptide
      pfam04802
      Location:168 → 359
      SMK-1; Component of IIS longevity pathway SMK-1
      cl17171
      Location:7 → 65
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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