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    ITGAM integrin subunit alpha M [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714832, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITGAMprovided by VGNC
    Official Full Name
    integrin subunit alpha Mprovided by VGNC
    Primary source
    VGNC:VGNC:99519
    See related
    Ensembl:ENSMMUG00000044324
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITGAM in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (28696099..28790176)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (29103584..29184178)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene PYD and CARD domain containing Neighboring gene tripartite motif containing 72 Neighboring gene pyrin domain containing 1 Neighboring gene U7 small nuclear RNA Neighboring gene la-related protein 1B-like Neighboring gene uncharacterized LOC114674433 Neighboring gene integrin subunit alpha X Neighboring gene integrin subunit alpha D Neighboring gene cytochrome c oxidase subunit 6A2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-M

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      28696099..28790176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840633.1 → XP_028696466.1  integrin alpha-M isoform X5

      UniProtKB/TrEMBL
      G7NQZ0
      Conserved Domains (4) summary
      smart00191
      Location:491 → 545
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:123 → 298
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam00357
      Location:1112 → 1126
      Integrin_alpha; Integrin alpha cytoplasmic region
      pfam08441
      Location:596 → 960
      Integrin_alpha2; Integrin alpha

    2. XM_028840631.1 → XP_028696464.1  integrin alpha-M isoform X1

      UniProtKB/TrEMBL
      G7NQZ0
      Conserved Domains (4) summary
      smart00191
      Location:515 → 569
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:147 → 322
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam00357
      Location:1136 → 1150
      Integrin_alpha; Integrin alpha cytoplasmic region
      pfam08441
      Location:620 → 984
      Integrin_alpha2; Integrin alpha

    3. XM_028840632.1 → XP_028696465.1  integrin alpha-M isoform X2

      UniProtKB/TrEMBL
      G7NQZ0
      Conserved Domains (4) summary
      smart00191
      Location:514 → 568
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:147 → 322
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam00357
      Location:1135 → 1149
      Integrin_alpha; Integrin alpha cytoplasmic region
      pfam08441
      Location:619 → 983
      Integrin_alpha2; Integrin alpha

    4. XM_015126018.2 → XP_014981504.2  integrin alpha-M isoform X3

      UniProtKB/TrEMBL
      G7NQZ0
      Conserved Domains (4) summary
      smart00191
      Location:515 → 570
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:147 → 322
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam00357
      Location:1129 → 1143
      Integrin_alpha; Integrin alpha cytoplasmic region
      pfam08441
      Location:613 → 977
      Integrin_alpha2; Integrin alpha

    5. XM_015126019.2 → XP_014981505.2  integrin alpha-M isoform X4

      UniProtKB/TrEMBL
      G7NQZ0
      Related
      ENSMMUP00000052151.2, ENSMMUT00000059078.2
      Conserved Domains (4) summary
      smart00191
      Location:514 → 569
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:147 → 322
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam00357
      Location:1128 → 1142
      Integrin_alpha; Integrin alpha cytoplasmic region
      pfam08441
      Location:612 → 976
      Integrin_alpha2; Integrin alpha
    Nucleotide Protein
    Heading Accession and Version

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