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    DTX4 deltex E3 ubiquitin ligase 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700410, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DTX4provided by VGNC
    Official Full Name
    deltex E3 ubiquitin ligase 4provided by VGNC
    Primary source
    VGNC:VGNC:71929
    See related
    Ensembl:ENSMMUG00000010277
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DTX4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (14719468..14755489, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (14821367..14857493, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene macrophage-expressed gene 1 protein-like Neighboring gene macrophage expressed 1 Neighboring gene FAM111 trypsin like peptidase A Neighboring gene FAM111 trypsin like peptidase B Neighboring gene uncharacterized LOC106993235

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase DTX4
    Names
    deltex homolog 4
    XP_001088765.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      14719468..14755489 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001088765.4 → XP_001088765.2  E3 ubiquitin-protein ligase DTX4

      UniProtKB/TrEMBL
      F6PVK0, H9EQY8
      Related
      ENSMMUP00000013449.4, ENSMMUT00000014359.4
      Conserved Domains (4) summary
      smart00678
      Location:8 → 86
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      PHA03247
      Location:167 → 431
      PHA03247; large tegument protein UL36; Provisional
      cd16671
      Location:406 → 472
      RING-H2_DTX1_4; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase deltex1 (DTX1), deltex4 (DTX4), and similar proteins
      pfam18102
      Location:475 → 609
      DTC; Deltex C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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