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    DPP4 dipeptidyl peptidase 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 654491, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DPP4provided by VGNC
    Official Full Name
    dipeptidyl peptidase 4provided by VGNC
    Primary source
    VGNC:VGNC:71979
    See related
    Ensembl:ENSMMUG00000008387
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DPP4 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (49061121..49145325, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (48722453..48807125, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene T-box brain transcription factor 1 Neighboring gene solute carrier family 4 member 10 Neighboring gene small nucleolar RNA U13 Neighboring gene glucagon Neighboring gene fibroblast activation protein alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4. van Doremalen N, et al. J Virol, 2014 Aug. PMID 24899185, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables dipeptidyl-peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dipeptidyl peptidase 4
    Names
    dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)
    dipeptidylpeptidase 4
    dipeptidylpeptidase IV
    NP_001034279.2
    XP_014965616.1
    XP_014965617.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039190.2 → NP_001034279.2  dipeptidyl peptidase 4

      See identical proteins and their annotated locations for NP_001034279.2

      Status: VALIDATED

      Source sequence(s)
      JU474559
      UniProtKB/TrEMBL
      F6VRB0, G7N865
      Related
      ENSMMUP00000011001.2, ENSMMUT00000011731.4
      Conserved Domains (2) summary
      pfam00326
      Location:559 → 763
      Peptidase_S9; Prolyl oligopeptidase family
      pfam00930
      Location:108 → 478
      DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      49061121..49145325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110130.2 → XP_014965616.1  dipeptidyl peptidase 4 isoform X1

      UniProtKB/TrEMBL
      G7N865
      Related
      ENSMMUP00000077781.1, ENSMMUT00000106855.1
      Conserved Domains (2) summary
      pfam00326
      Location:558 → 762
      Peptidase_S9; Prolyl oligopeptidase family
      pfam00930
      Location:107 → 477
      DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region

    2. XM_015110131.2 → XP_014965617.1  dipeptidyl peptidase 4 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AIP8
      Conserved Domains (3) summary
      COG1506
      Location:314 → 680
      DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
      pfam00326
      Location:475 → 679
      Peptidase_S9; Prolyl oligopeptidase family
      pfam00930
      Location:24 → 394
      DPPIV_N; Dipeptidyl peptidase IV (DPP IV) N-terminal region
    Nucleotide Protein
    Heading Accession and Version

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