MST1R macrophage stimulating 1 receptor [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: MST1Rprovided by VGNC
Official Full Name: macrophage stimulating 1 receptorprovided by VGNC
Primary source: VGNC:VGNC:74941
See related: Ensembl:ENSMMUG00000003353
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (106014549..106031735, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (92414920..92432594)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH18128 (e-PCR)
- UniSTS:73827

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables semaphorin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane receptor protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell surface receptor protein tyrosine kinase signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phagocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of axonogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info	PubMed
involved_in semaphorin-plexin signaling pathway involved in axon guidance	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of semaphorin receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: macrophage-stimulating protein receptor

Names: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

XP_014986372.2

EC 2.7.10.1

XP_014986373.2

EC 2.7.10.1

XP_014986374.2

EC 2.7.10.1

XP_014986376.2

EC 2.7.10.1

XP_014986377.2

EC 2.7.10.1

XP_014986378.2

EC 2.7.10.1

XP_014986379.2

EC 2.7.10.1

XP_014986380.2

EC 2.7.10.1

XP_014986381.2

EC 2.7.10.1

XP_014986382.2

EC 2.7.10.1

XP_014986383.2

EC 2.7.10.1

XP_014986384.2

EC 2.7.10.1

XP_014986385.2

EC 2.7.10.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041755.1 Reference Mmul_10 Primary Assembly

Range

106014549..106031735 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015130894.2 → XP_014986380.2 macrophage-stimulating protein receptor isoform X8

UniProtKB/TrEMBL

A0A5S6RBZ8, A0A8J8Y7X0, F7ED27, G7ML80

Related

ENSMMUP00000004467.4, ENSMMUT00000004739.4

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:769 → 829

IPT; ig-like, plexins, transcription factors

cd01179
Location:684 → 768

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cd05058
Location:1085 → 1346

PTKc_Met_Ron; Catalytic domain of the Protein Tyrosine Kinases, Met and Ron

cl15674
Location:569 → 683

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
XM_015130897.2 → XP_014986383.2 macrophage-stimulating protein receptor isoform X11

UniProtKB/TrEMBL

F7ED42

Related

ENSMMUP00000004466.4, ENSMMUT00000004738.4

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:769 → 829

IPT; ig-like, plexins, transcription factors

cd01179
Location:684 → 768

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cd01180
Location:569 → 683

IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cd05058
Location:1036 → 1297

PTKc_Met_Ron; Catalytic domain of the Protein Tyrosine Kinases, Met and Ron
XM_015130888.2 → XP_014986374.2 macrophage-stimulating protein receptor isoform X3

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:769 → 830

IPT; ig-like, plexins, transcription factors

cd01179
Location:684 → 768

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 683

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1086 → 1406

PKc_like; Protein Kinases, catalytic domain
XM_015130892.2 → XP_014986378.2 macrophage-stimulating protein receptor isoform X6

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 836

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1043 → 1363

PKc_like; Protein Kinases, catalytic domain
XM_015130887.2 → XP_014986373.2 macrophage-stimulating protein receptor isoform X2

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 836

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1092 → 1412

PKc_like; Protein Kinases, catalytic domain
XM_015130896.2 → XP_014986382.2 macrophage-stimulating protein receptor isoform X10

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cd05058
Location:1044 → 1305

PTKc_Met_Ron; Catalytic domain of the Protein Tyrosine Kinases, Met and Ron

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
XM_015130891.2 → XP_014986377.2 macrophage-stimulating protein receptor isoform X5

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1044 → 1364

PKc_like; Protein Kinases, catalytic domain
XM_015130890.2 → XP_014986376.2 macrophage-stimulating protein receptor isoform X4

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1053 → 1373

PKc_like; Protein Kinases, catalytic domain
XM_015130898.2 → XP_014986384.2 macrophage-stimulating protein receptor isoform X12

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cd05058
Location:1028 → 1286

PTKc_Met_Ron; Catalytic domain of the Protein Tyrosine Kinases, Met and Ron

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
XM_015130895.2 → XP_014986381.2 macrophage-stimulating protein receptor isoform X9

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1028 → 1345

PKc_like; Protein Kinases, catalytic domain
XM_015130893.2 → XP_014986379.2 macrophage-stimulating protein receptor isoform X7

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cd05058
Location:1093 → 1354

PTKc_Met_Ron; Catalytic domain of the Protein Tyrosine Kinases, Met and Ron

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
XM_015130886.2 → XP_014986372.2 macrophage-stimulating protein receptor isoform X1

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1093 → 1413

PKc_like; Protein Kinases, catalytic domain
XM_015130899.2 → XP_014986385.2 macrophage-stimulating protein receptor isoform X13

Conserved Domains (6) summary

cd11279
Location:27 → 523

Sema_RON; The Sema domain, a protein interacting module, of RON Receptor Tyrosine Kinase

smart00423
Location:526 → 568

PSI; domain found in Plexins, Semaphorins and Integrins

smart00429
Location:776 → 837

IPT; ig-like, plexins, transcription factors

cd01179
Location:691 → 775

IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...

cl15674
Location:569 → 690

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

cl21453
Location:1093 → 1125

PKc_like; Protein Kinases, catalytic domain