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    GCN1 GCN1 activator of EIF2AK4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698528, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GCN1provided by VGNC
    Official Full Name
    GCN1 activator of EIF2AK4provided by VGNC
    Primary source
    VGNC:VGNC:72905
    Locus tag
    EGK_04253
    See related
    Ensembl:ENSMMUG00000009152
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GCN1L1
    Orthologs
    human mouse all
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    Genomic context

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    See GCN1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    58
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (119906202..119974890, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (120335320..120403416, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene RAB35, member RAS oncogene family Neighboring gene uncharacterized LOC114670969 Neighboring gene ribosomal protein lateral stalk subunit P0 Neighboring gene paxillin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to amino acid starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eIF-2-alpha kinase activator GCN1
    Names
    GCN1 general control of amino-acid synthesis 1-like 1
    GCN1, eIF2 alpha kinase activator homolog
    translational activator GCN1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      119906202..119974890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152948.2 → XP_015008434.1  eIF-2-alpha kinase activator GCN1 isoform X1

      UniProtKB/TrEMBL
      H9FP65, I0FNS6
      Conserved Domains (4) summary
      cd00020
      Location:1504 → 1607
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam12074
      Location:356 → 711
      DUF3554; Domain of unknown function (DUF3554)
      pfam13646
      Location:1622 → 1727
      HEAT_2; HEAT repeats
      sd00044
      Location:1467 → 1491
      HEAT; HEAT repeat [structural motif]

    2. XM_015152949.2 → XP_015008435.1  eIF-2-alpha kinase activator GCN1 isoform X2

      UniProtKB/TrEMBL
      A0A5K1VRX8, H9FP65, I0FNS6
      Related
      ENSMMUP00000058844.1, ENSMMUT00000055941.2
      Conserved Domains (4) summary
      cd00020
      Location:1498 → 1601
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam12074
      Location:356 → 705
      DUF3554; Domain of unknown function (DUF3554)
      pfam13646
      Location:1616 → 1721
      HEAT_2; HEAT repeats
      sd00044
      Location:1461 → 1485
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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