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    ACVR1B activin A receptor type 1B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696587, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ACVR1Bprovided by VGNC
    Official Full Name
    activin A receptor type 1Bprovided by VGNC
    Primary source
    VGNC:VGNC:69446
    See related
    Ensembl:ENSMMUG00000046877
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ACVR1B in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (51556621..51602286)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (50253499..50299153)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene activin A receptor like type 1 Neighboring gene uncharacterized LOC114670848 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114670850 Neighboring gene uncharacterized LOC114670849 Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene vegetative cell wall protein gp1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables activin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables activin receptor activity, type I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of activin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    activin receptor type-1B
    Names
    activin A receptor, type IB
    NP_001252559.1
    XP_015007101.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265630.1 → NP_001252559.1  activin receptor type-1B precursor

      See identical proteins and their annotated locations for NP_001252559.1

      Status: PROVISIONAL

      Source sequence(s)
      JV667500
      UniProtKB/TrEMBL
      A0A1D5QW72, H9FCI5, I2CYX8
      Related
      ENSMMUP00000052302.2, ENSMMUT00000073392.2
      Conserved Domains (3) summary
      cd14143
      Location:211 → 498
      STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
      pfam01064
      Location:32 → 105
      Activin_recp; Activin types I and II receptor domain
      pfam08515
      Location:178 → 205
      TGF_beta_GS; Transforming growth factor beta type I GS-motif

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      51556621..51602286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151615.2 → XP_015007101.1  activin receptor type-1B isoform X1

      UniProtKB/TrEMBL
      H9FCI5
      Conserved Domains (2) summary
      smart00467
      Location:125 → 155
      GS; GS motif
      cd14143
      Location:159 → 446
      STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials