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    EPS8L2 EPS8 signaling adaptor L2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720824, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPS8L2provided by VGNC
    Official Full Name
    EPS8 signaling adaptor L2provided by VGNC
    Primary source
    VGNC:VGNC:72081
    See related
    Ensembl:ENSMMUG00000017483
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EPS8L2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (766056..786444)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (557827..578689)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672196 Neighboring gene DEAF1 transcription factor Neighboring gene transmembrane protein 80 Neighboring gene transaldolase 1 Neighboring gene glutamine amidotransferase class 1 domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ruffle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    epidermal growth factor receptor kinase substrate 8-like protein 2
    Names
    EPS8 like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      766056..786444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832980.1 → XP_028688813.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:667 → 732
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    2. XM_028832977.1 → XP_028688810.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:667 → 732
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    3. XM_028832983.1 → XP_028688816.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:622 → 687
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:451 → 501
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:3 → 133
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    4. XM_028832976.1 → XP_028688809.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:667 → 732
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    5. XM_028832982.1 → XP_028688815.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X2

      Conserved Domains (3) summary
      cd09540
      Location:647 → 712
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:476 → 526
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cl17171
      Location:139 → 161
      PH-like; Pleckstrin homology-like domain

    6. XM_028832979.1 → XP_028688812.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:667 → 732
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    7. XM_015113252.2 → XP_014968738.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5R0H5, F6VIA6
      Related
      ENSMMUP00000023008.4, ENSMMUT00000024581.4
      Conserved Domains (3) summary
      cd09540
      Location:623 → 688
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    8. XM_028832978.1 → XP_028688811.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:667 → 732
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain

    9. XM_028832981.1 → XP_028688814.1  epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R0H5
      Conserved Domains (3) summary
      cd09540
      Location:667 → 732
      SAM_EPS8-like; SAM domain of EPS8-like subfamily
      cd11764
      Location:496 → 546
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:48 → 178
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
    Nucleotide Protein
    Heading Accession and Version

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