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    UBE2K ubiquitin conjugating enzyme E2 K [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699734, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UBE2Kprovided by VGNC
    Official Full Name
    ubiquitin conjugating enzyme E2 Kprovided by VGNC
    Primary source
    VGNC:VGNC:79957
    Locus tag
    EGK_15661
    See related
    Ensembl:ENSMMUG00000011325
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    HIP2
    Orthologs
    human mouse all
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    Genomic context

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    See UBE2K in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (38821227..38907212)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (39386336..39472392)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 14 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC114678154 Neighboring gene PDS5 cohesin associated factor A Neighboring gene keratin, type I cytoskeletal 18 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme E2 K
    Names
    huntingtin interacting protein 2
    ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
    NP_001247770.1
    XP_014993648.1
    XP_028703849.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260841.2 → NP_001247770.1  ubiquitin-conjugating enzyme E2 K

      See identical proteins and their annotated locations for NP_001247770.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046905
      UniProtKB/TrEMBL
      A0A8J8YDV8, F6UEX6, G7MSS4, H9FAT8
      Related
      ENSMMUP00000014859.2, ENSMMUT00000015858.4
      Conserved Domains (2) summary
      cd00195
      Location:6 → 149
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
      cd14390
      Location:163 → 200
      UBA_II_E2_UBE2K; UBA domain of vertebrate ubiquitin-conjugating enzyme E2 K (UBE2K)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      38821227..38907212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015138162.2 → XP_014993648.1  ubiquitin-conjugating enzyme E2 K isoform X1

      UniProtKB/TrEMBL
      H9FAT9
      Conserved Domains (2) summary
      cd00195
      Location:6 → 133
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
      cl21463
      Location:132 → 157
      UBA_like_SF; UBA domain-like superfamily

    2. XM_028848016.1 → XP_028703849.1  ubiquitin-conjugating enzyme E2 K isoform X2

      Conserved Domains (2) summary
      cl00154
      Location:1 → 51
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
      cl21463
      Location:60 → 97
      UBA_like_SF; UBA domain-like superfamily
    Nucleotide Protein
    Heading Accession and Version

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