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    AGO3 argonaute RISC catalytic component 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712543, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AGO3provided by VGNC
    Official Full Name
    argonaute RISC catalytic component 3provided by VGNC
    Primary source
    VGNC:VGNC:99838
    See related
    Ensembl:ENSMMUG00000006252
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    EIF2C3
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    Genomic context

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    See AGO3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (188526445..188667129, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (35112135..35241591)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene magnesium transporter protein 1 pseudogene Neighboring gene tektin 2 Neighboring gene argonaute RISC component 1 Neighboring gene argonaute RISC component 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of stem cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulatory ncRNA-mediated gene silencing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein argonaute-3
    Names
    argonaute 3, RISC catalytic component
    eukaryotic translation initiation factor 2C, 3
    XP_014990770.1
    XP_014990777.1
    XP_014990783.1
    XP_014990791.1
    XP_014990799.1
    XP_028691864.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      188526445..188667129 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028836031.1 → XP_028691864.1  protein argonaute-3 isoform X2

      UniProtKB/TrEMBL
      G7MFV3
      Conserved Domains (4) summary
      cd02846
      Location:228 → 348
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:393 → 818
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:177 → 227
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:73 → 167
      ArgoN; N-terminal domain of argonaute

    2. XM_015135291.1 → XP_014990777.1  protein argonaute-3 isoform X3

      Conserved Domains (2) summary
      cd02846
      Location:1 → 114
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:159 → 584
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...

    3. XM_015135297.2 → XP_014990783.1  protein argonaute-3 isoform X3

      Conserved Domains (2) summary
      cd02846
      Location:1 → 114
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:159 → 584
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...

    4. XM_015135313.2 → XP_014990799.1  protein argonaute-3 isoform X3

      Conserved Domains (2) summary
      cd02846
      Location:1 → 114
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:159 → 584
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...

    5. XM_015135305.2 → XP_014990791.1  protein argonaute-3 isoform X3

      Conserved Domains (2) summary
      cd02846
      Location:1 → 114
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:159 → 584
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...

    6. XM_015135284.2 → XP_014990770.1  protein argonaute-3 isoform X1

      UniProtKB/TrEMBL
      G7MFV3, H9Z073
      Related
      ENSMMUP00000051045.1, ENSMMUT00000071036.2
      Conserved Domains (4) summary
      cd02846
      Location:228 → 348
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:393 → 818
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:177 → 227
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:73 → 167
      ArgoN; N-terminal domain of argonaute
    Nucleotide Protein
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