MID1 midline 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: MID1provided by VGNC
Official Full Name: midline 1provided by VGNC
Primary source: VGNC:VGNC:74721
See related: Ensembl:ENSMMUG00000020179
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	X	NC_041774.1 (10025730..10416839, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	X	NC_027913.1 (9518042..9908895, complement)

Chromosome X - NC_041774.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-84226 (e-PCR)
- UniSTS:104714

A004G38 (e-PCR)
- UniSTS:36108

SHGC-83251 (e-PCR)
- UniSTS:101138

PMC15848P1 (e-PCR)
- UniSTS:271436

AF003639 (e-PCR)
- UniSTS:94578

RH65878 (e-PCR)
- UniSTS:76155

AF003649 (e-PCR)
- UniSTS:94588

RH65583 (e-PCR)
- UniSTS:75656

AF003663 (e-PCR)
- UniSTS:94602

AF003674 (e-PCR)
- UniSTS:94613

DXS1438 (e-PCR)
- UniSTS:99221

AF003676 (e-PCR)
- UniSTS:94615

AF003682 (e-PCR)
- UniSTS:94621

AF003683 (e-PCR)
- UniSTS:94622

DXS7713 (e-PCR)
- UniSTS:81071

RH99148 (e-PCR)
- UniSTS:85976

SHGC-36657 (e-PCR)
- UniSTS:44777

MID1 (e-PCR)
- UniSTS:498175

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase Midline-1

Names: midline 1 (Opitz/BBB syndrome)

XP_001093502.2

EC 2.3.2.27

XP_014982415.2

EC 2.3.2.27

XP_014982416.2

EC 2.3.2.27

XP_014982417.2

EC 2.3.2.27

XP_028698130.1

EC 2.3.2.27

XP_028698131.1

EC 2.3.2.27

XP_028698132.1

EC 2.3.2.27

XP_028698133.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041774.1 Reference Mmul_10 Primary Assembly

Range

10025730..10416839 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028842299.1 → XP_028698132.1 E3 ubiquitin-protein ligase Midline-1 isoform X2

Conserved Domains (6) summary

smart00502
Location:182 → 306

BBC; B-Box C-terminal domain

cd00063
Location:343 → 443

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:447 → 623

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:285 → 336

COS; TRIM C-terminal subgroup One Signature domain
XM_015126930.2 → XP_014982416.2 E3 ubiquitin-protein ligase Midline-1 isoform X1

UniProtKB/TrEMBL

A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86

Conserved Domains (7) summary

smart00502
Location:219 → 344

BBC; B-Box C-terminal domain

cd00063
Location:381 → 481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:485 → 661

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19822
Location:168 → 214

Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:323 → 374

COS; TRIM C-terminal subgroup One Signature domain
XM_015126931.2 → XP_014982417.2 E3 ubiquitin-protein ligase Midline-1 isoform X1

UniProtKB/TrEMBL

A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86

Conserved Domains (7) summary

smart00502
Location:219 → 344

BBC; B-Box C-terminal domain

cd00063
Location:381 → 481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:485 → 661

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19822
Location:168 → 214

Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:323 → 374

COS; TRIM C-terminal subgroup One Signature domain
XM_028842298.1 → XP_028698131.1 E3 ubiquitin-protein ligase Midline-1 isoform X1

UniProtKB/TrEMBL

A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86

Conserved Domains (7) summary

smart00502
Location:219 → 344

BBC; B-Box C-terminal domain

cd00063
Location:381 → 481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:485 → 661

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19822
Location:168 → 214

Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:323 → 374

COS; TRIM C-terminal subgroup One Signature domain
XM_028842300.1 → XP_028698133.1 E3 ubiquitin-protein ligase Midline-1 isoform X2

Conserved Domains (6) summary

smart00502
Location:182 → 306

BBC; B-Box C-terminal domain

cd00063
Location:343 → 443

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:447 → 623

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:285 → 336

COS; TRIM C-terminal subgroup One Signature domain
XM_015126929.2 → XP_014982415.2 E3 ubiquitin-protein ligase Midline-1 isoform X1

UniProtKB/TrEMBL

A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86

Conserved Domains (7) summary

smart00502
Location:219 → 344

BBC; B-Box C-terminal domain

cd00063
Location:381 → 481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:485 → 661

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19822
Location:168 → 214

Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:323 → 374

COS; TRIM C-terminal subgroup One Signature domain
XM_028842297.1 → XP_028698130.1 E3 ubiquitin-protein ligase Midline-1 isoform X1

UniProtKB/TrEMBL

A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86

Conserved Domains (7) summary

smart00502
Location:219 → 344

BBC; B-Box C-terminal domain

cd00063
Location:381 → 481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:485 → 661

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19822
Location:168 → 214

Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:323 → 374

COS; TRIM C-terminal subgroup One Signature domain
XM_001093502.4 → XP_001093502.2 E3 ubiquitin-protein ligase Midline-1 isoform X1

UniProtKB/TrEMBL

A0A5S6RD33, A0A8J8XLX7, F6WCI4, G7NS86

Related

ENSMMUP00000007446.4, ENSMMUT00000007921.4

Conserved Domains (7) summary

smart00502
Location:219 → 344

BBC; B-Box C-terminal domain

cd00063
Location:381 → 481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd12892
Location:485 → 661

SPRY_PRY_TRIM18; PRY/SPRY domain of TRIM18/MID1, also known as FXY or RNF59

cd16753
Location:8 → 61

RING-HC_MID1; RING finger, HC subclass, found in midline-1 (MID1) and similar proteins

cd19822
Location:168 → 214

Bbox2_MID1_C-I; B-box-type 2 zinc finger found in midline-1 (MID1) and similar proteins

cd19836
Location:115 → 164

Bbox1_MID1_C-I; B-box-type 1 zinc finger found in midline-1 (MID1) and similar proteins

pfam18568
Location:323 → 374

COS; TRIM C-terminal subgroup One Signature domain