U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    VARS1 valyl-tRNA synthetase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715537, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    VARS1provided by VGNC
    Official Full Name
    valyl-tRNA synthetase 1provided by VGNC
    Primary source
    VGNC:VGNC:78755
    Locus tag
    EGK_14727
    See related
    Ensembl:ENSMMUG00000006828
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    VARS; VARS2; VARS2L
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See VARS1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (137707454..137726508)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (32645657..32664681, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene heat shock protein family A (Hsp70) member 1A Neighboring gene heat shock protein family A (Hsp70) member 1 like Neighboring gene uncharacterized LOC106997897 Neighboring gene LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene von Willebrand factor A domain containing 7 Neighboring gene suppressor APC domain containing 1 Neighboring gene mutS homolog 5

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genomic evolution of MHC class I region in primates. Fukami-Kobayashi K, et al. Proc Natl Acad Sci U S A, 2005 Jun 28. PMID 15967992, Free PMC Article
    2. Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex. Kulski JK, et al. Mol Biol Evol, 2004 Nov. PMID 15269276
    3. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. Shiina T, et al. Genetics, 2006 Jul. PMID 16702430, Free PMC Article
    4. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables valine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in valyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    valine--tRNA ligase, mitochondrial
    Names
    Valyl-tRNA synthetase, mitochondrial
    valine--tRNA ligase
    valyl-tRNA synthetase 2, mitochondrial (putative)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      137707454..137726508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136000.2 → XP_014991486.1  valine--tRNA ligase, mitochondrial isoform X1

      Conserved Domains (7) summary
      cd07962
      Location:939 → 1076
      Anticodon_Ia_Val; Anticodon-binding domain of valyl tRNA synthetases
      cd00817
      Location:336 → 939
      ValRS_core; catalytic core domain of valyl-tRNA synthetases
      cd10294
      Location:92 → 213
      GST_C_ValRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of vertebrate Valyl-tRNA synthetase
      COG0625
      Location:56 → 203
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      PTZ00419
      Location:283 → 1265
      PTZ00419; valyl-tRNA synthetase-like protein; Provisional
      pfam10458
      Location:1197 → 1259
      Val_tRNA-synt_C; Valyl tRNA synthetase tRNA binding arm
      pfam13603
      Location:514 → 610
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2

    2. XM_015136001.2 → XP_014991487.1  valine--tRNA ligase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A5F8A6S7, A0A8J8XAC5, F7GXM4, G7MRK4
      Related
      ENSMMUP00000008979.3, ENSMMUT00000009554.4
      Conserved Domains (7) summary
      cd07962
      Location:938 → 1075
      Anticodon_Ia_Val; Anticodon-binding domain of valyl tRNA synthetases
      cd00817
      Location:335 → 938
      ValRS_core; catalytic core domain of valyl-tRNA synthetases
      cd10294
      Location:92 → 213
      GST_C_ValRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of vertebrate Valyl-tRNA synthetase
      COG0625
      Location:56 → 203
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      PTZ00419
      Location:282 → 1264
      PTZ00419; valyl-tRNA synthetase-like protein; Provisional
      pfam10458
      Location:1196 → 1258
      Val_tRNA-synt_C; Valyl tRNA synthetase tRNA binding arm
      pfam13603
      Location:513 → 609
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.