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    MAP3K6 mitogen-activated protein kinase kinase kinase 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715911, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAP3K6provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase 6provided by VGNC
    Primary source
    VGNC:VGNC:74496
    See related
    Ensembl:ENSMMUG00000018318
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (197367276..197380286)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (26219941..26232953, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 3 Neighboring gene CD164 molecule like 2 Neighboring gene ficolin 3 Neighboring gene synaptotagmin like 1 Neighboring gene transmembrane protein 222 Neighboring gene actin, muscle-like Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 6
    XP_001111161.3
    XP_014988149.2
    XP_028693202.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      197367276..197380286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001111161.4 → XP_001111161.3  mitogen-activated protein kinase kinase kinase 6 isoform X1

      UniProtKB/TrEMBL
      F7HFE8
      Related
      ENSMMUP00000024083.4, ENSMMUT00000025743.4
      Conserved Domains (2) summary
      cd06624
      Location:640 → 907
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 507
      DUF4071; Domain of unknown function (DUF4071)

    2. XM_015132663.2 → XP_014988149.2  mitogen-activated protein kinase kinase kinase 6 isoform X2

      UniProtKB/TrEMBL
      F7HFE8
      Related
      ENSMMUP00000054447.2, ENSMMUT00000070831.2
      Conserved Domains (2) summary
      cd06624
      Location:632 → 899
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:129 → 499
      DUF4071; Domain of unknown function (DUF4071)

    3. XM_028837369.1 → XP_028693202.1  mitogen-activated protein kinase kinase kinase 6 isoform X3

      UniProtKB/TrEMBL
      F7HFE8
      Conserved Domains (2) summary
      cd06624
      Location:500 → 767
      STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
      pfam13281
      Location:1 → 367
      DUF4071; Domain of unknown function (DUF4071)
    Nucleotide Protein
    Heading Accession and Version

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