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    NR4A2 nuclear receptor subfamily 4 group A member 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697077, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NR4A2provided by VGNC
    Official Full Name
    nuclear receptor subfamily 4 group A member 2provided by VGNC
    Primary source
    VGNC:VGNC:75518
    Locus tag
    EGK_04449
    See related
    Ensembl:ENSMMUG00000011607
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NR4A2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (43420121..43428427, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (43084662..43092951, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene heme-binding protein 2 pseudogene Neighboring gene 60S ribosomal protein L10-like Neighboring gene transfer RNA alanine (anticodon CGC) Neighboring gene transfer RNA glycine (anticodon GCC)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear glucocorticoid receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to corticotropin-releasing hormone stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in dopaminergic neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear receptor subfamily 4 group A member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266910.2 → NP_001253839.1  nuclear receptor subfamily 4 group A member 2

      See identical proteins and their annotated locations for NP_001253839.1

      Status: PROVISIONAL

      Source sequence(s)
      JU471923
      UniProtKB/TrEMBL
      A0A1D5Q5P9, A0A1D5QQI7, A0A5S6RAC6, A0A8J8Y407, G7N845
      Related
      ENSMMUP00000050315.2, ENSMMUT00000062758.2
      Conserved Domains (2) summary
      cd07071
      Location:361 → 598
      NR_LBD_Nurr1; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
      cd06969
      Location:261 → 335
      NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      43420121..43428427 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110134.2 → XP_014965620.1  nuclear receptor subfamily 4 group A member 2 isoform X3

      Conserved Domains (2) summary
      cd07071
      Location:298 → 535
      NR_LBD_Nurr1; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
      cd06969
      Location:198 → 272
      NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

    2. XM_015110132.2 → XP_014965618.1  nuclear receptor subfamily 4 group A member 2 isoform X1

      Conserved Domains (2) summary
      cd06969
      Location:261 → 335
      NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B
      cl11397
      Location:362 → 573
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    3. XM_015110133.2 → XP_014965619.1  nuclear receptor subfamily 4 group A member 2 isoform X2

      UniProtKB/TrEMBL
      F6PLH4
      Conserved Domains (2) summary
      cd06969
      Location:261 → 335
      NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B
      cl11397
      Location:367 → 477
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    RNA

    1. XR_001438584.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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