U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FLOT1 flotillin 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714175, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FLOT1provided by VGNC
    Official Full Name
    flotillin 1provided by VGNC
    Primary source
    VGNC:VGNC:72674
    Locus tag
    EGK_14682
    See related
    Ensembl:ENSMMUG00000014071
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FLOT1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (139171965..139183851)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (31431752..31443559, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677649 Neighboring gene basic proline-rich protein-like Neighboring gene immediate early response 3 Neighboring gene tubulin beta class I Neighboring gene mediator of DNA damage checkpoint 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genomic evolution of MHC class I region in primates. Fukami-Kobayashi K, et al. Proc Natl Acad Sci U S A, 2005 Jun 28. PMID 15967992, Free PMC Article
    2. Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex. Kulski JK, et al. Mol Biol Evol, 2004 Nov. PMID 15269276
    3. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. Shiina T, et al. Genetics, 2006 Jul. PMID 16702430, Free PMC Article
    4. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    5. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of cell junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell-cell adhesion mediated by cadherin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein kinase C signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of receptor internalization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    flotillin-1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105168.1 → NP_001098638.1  flotillin-1

      See identical proteins and their annotated locations for NP_001098638.1

      Status: PROVISIONAL

      Source sequence(s)
      AB128049
      UniProtKB/Swiss-Prot
      Q5TM70
      UniProtKB/TrEMBL
      A0A8J8Y099, F7AFR3, G7MRG3, H9FNJ4, H9Z453
      Conserved Domains (2) summary
      COG2268
      Location:4 → 419
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:30 → 175
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      139171965..139183851
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135857.2 → XP_014991343.1  flotillin-1 isoform X1

      UniProtKB/Swiss-Prot
      Q5TM70
      UniProtKB/TrEMBL
      A0A8J8Y099, F7AFR3, G7MRG3, H9FNJ4, H9Z453
      Related
      ENSMMUP00000077941.1, ENSMMUT00000109749.1
      Conserved Domains (2) summary
      COG2268
      Location:4 → 419
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:30 → 175
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. XM_028846808.1 → XP_028702641.1  flotillin-1 isoform X2

      UniProtKB/TrEMBL
      H9Z453
      Conserved Domains (2) summary
      COG2268
      Location:3 → 340
      YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
      cd03399
      Location:1 → 96
      SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5TM70.1 GenPept UniProtKB/Swiss-Prot:Q5TM70

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.