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    PAK5 p21 (RAC1) activated kinase 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719458, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PAK5provided by VGNC
    Official Full Name
    p21 (RAC1) activated kinase 5provided by VGNC
    Primary source
    VGNC:VGNC:97111
    Locus tag
    EGK_02663
    See related
    Ensembl:ENSMMUG00000003275
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PAK5 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (56680502..56983096)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (42488605..42789639, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000470 Neighboring gene uncharacterized LOC107000488 Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene phospholipase C beta 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PAK 5
    Names
    Serine/threonine-protein kinase PAK 7
    p21(CDKN1A)-activated kinase 7
    NP_001247916.1
    XP_015004871.1
    XP_028683287.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260987.1 → NP_001247916.1  serine/threonine-protein kinase PAK 5

      See identical proteins and their annotated locations for NP_001247916.1

      Status: PROVISIONAL

      Source sequence(s)
      JU321969
      UniProtKB/TrEMBL
      A0A5F8AT53, A0A8J8Y8P6, F7FKL1, G7N2Y5
      Related
      ENSMMUP00000004366.2, ENSMMUT00000004632.4
      Conserved Domains (2) summary
      cd06658
      Location:426 → 717
      STKc_PAK5; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 5
      cd01093
      Location:9 → 55
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      56680502..56983096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015149385.2 → XP_015004871.1  serine/threonine-protein kinase PAK 5 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AT53, A0A8J8Y8P6, F7FKL1, G7N2Y5
      Related
      ENSMMUP00000073922.1, ENSMMUT00000108027.1
      Conserved Domains (2) summary
      cd06658
      Location:426 → 717
      STKc_PAK5; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 5
      cd01093
      Location:9 → 55
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...

    2. XM_028827454.1 → XP_028683287.1  serine/threonine-protein kinase PAK 5 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AT53, A0A8J8Y8P6, F7FKL1, G7N2Y5
      Related
      ENSMMUP00000061937.1, ENSMMUT00000106148.1
      Conserved Domains (2) summary
      cd06658
      Location:426 → 717
      STKc_PAK5; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 5
      cd01093
      Location:9 → 55
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    Nucleotide Protein
    Heading Accession and Version

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