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    SOX2 SRY-box transcription factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707039, updated on 5-Mar-2024

    Summary

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    Gene symbol
    SOX2
    Gene description
    SRY-box transcription factor 2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SOX2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (86874371..87004602)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (111229904..111445753, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676301 Neighboring gene uncharacterized LOC106996989 Neighboring gene uncharacterized LOC114676302 Neighboring gene uncharacterized LOC114676303

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Liu H, et al. Cell Stem Cell, 2008 Dec 4. PMID 19041774
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor SOX-2
    Names
    SRY (sex determining region Y)-box 2
    SRY-box 2
    sex determining region Y-box 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142940.1 → NP_001136412.1  transcription factor SOX-2

      See identical proteins and their annotated locations for NP_001136412.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ375750
      UniProtKB/TrEMBL
      B8XIA2, H9FYU8
      Conserved Domains (2) summary
      cd01388
      Location:42 → 113
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam12336
      Location:112 → 202
      SOXp; SOX transcription factor

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      86874371..87004602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843258.1 → XP_028699091.1  transcription factor SOX-2 isoform X1

      UniProtKB/TrEMBL
      B8XIA2, H9FYU8
      Conserved Domains (2) summary
      cd01388
      Location:42 → 113
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam12336
      Location:112 → 202
      SOXp; SOX transcription factor

    2. XM_028843259.1 → XP_028699092.1  transcription factor SOX-2 isoform X1

      UniProtKB/TrEMBL
      B8XIA2, H9FYU8
      Conserved Domains (2) summary
      cd01388
      Location:42 → 113
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam12336
      Location:112 → 202
      SOXp; SOX transcription factor

    3. XM_028843257.1 → XP_028699090.1  transcription factor SOX-2 isoform X1

      UniProtKB/TrEMBL
      B8XIA2, H9FYU8
      Conserved Domains (2) summary
      cd01388
      Location:42 → 113
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam12336
      Location:112 → 202
      SOXp; SOX transcription factor

    RNA

    1. XR_001443080.2 RNA Sequence

    2. XR_001443084.2 RNA Sequence

    3. XR_003726936.1 RNA Sequence

    4. XR_003726935.1 RNA Sequence

    5. XR_001443079.2 RNA Sequence

    6. XR_001443083.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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