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    RGL1 ral guanine nucleotide dissociation stimulator like 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717554, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RGL1provided by VGNC
    Official Full Name
    ral guanine nucleotide dissociation stimulator like 1provided by VGNC
    Primary source
    VGNC:VGNC:76868
    Locus tag
    EGK_01860
    See related
    Ensembl:ENSMMUG00000016399
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RGL1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (40896859..41187890)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (183330102..183672207, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114679499 Neighboring gene SMG7 nonsense mediated mRNA decay factor Neighboring gene neutrophil cytosolic factor 2 Neighboring gene actin related protein 2/3 complex subunit 5 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 Neighboring gene uncharacterized LOC114679512 Neighboring gene collagen beta(1-O)galactosyltransferase 2 Neighboring gene tRNA splicing endonuclease subunit 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ral guanine nucleotide dissociation stimulator-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266879.1 → NP_001253808.1  ral guanine nucleotide dissociation stimulator-like 1

      See identical proteins and their annotated locations for NP_001253808.1

      Status: PROVISIONAL

      Source sequence(s)
      JU321481
      UniProtKB/TrEMBL
      A0A5F7ZHA5, A0A8J8Y6J3, F7FZA2, G7MF33
      Related
      ENSMMUP00000021538.2, ENSMMUT00000023027.4
      Conserved Domains (3) summary
      smart00229
      Location:100 → 231
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:263 → 532
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd17210
      Location:682 → 768
      RA_RGL; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) and similar proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      40896859..41187890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015121590.2 → XP_014977076.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZHA5, A0A5F7ZII8
      Related
      ENSMMUP00000064995.1, ENSMMUT00000090691.1
      Conserved Domains (3) summary
      cd00153
      Location:646 → 731
      RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
      smart00229
      Location:63 → 194
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:226 → 495
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    2. XM_028845858.1 → XP_028701691.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHA5, A0A8J8Y6J3, F7FZA2, G7MF33
      Conserved Domains (3) summary
      smart00229
      Location:100 → 231
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:263 → 532
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd17210
      Location:682 → 768
      RA_RGL; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) and similar proteins

    3. XM_028845860.1 → XP_028701693.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZHA5, A0A8J8Y6J3, F7FZA2, G7MF33
      Related
      ENSMMUP00000064014.1, ENSMMUT00000104072.1
      Conserved Domains (3) summary
      smart00229
      Location:100 → 231
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:263 → 532
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd17210
      Location:682 → 768
      RA_RGL; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) and similar proteins

    4. XM_015121585.2 → XP_014977071.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZHA5, F7FYX4
      Related
      ENSMMUP00000021540.2, ENSMMUT00000023029.4
      Conserved Domains (3) summary
      cd00153
      Location:648 → 733
      RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
      smart00229
      Location:65 → 196
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:228 → 497
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    Nucleotide Protein
    Heading Accession and Version

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