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    CHRM5 cholinergic receptor muscarinic 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574330, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CHRM5provided by VGNC
    Official Full Name
    cholinergic receptor muscarinic 5provided by VGNC
    Primary source
    VGNC:VGNC:71044
    Locus tag
    EGK_17314
    See related
    Ensembl:ENSMMUG00000014227
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CHRM5 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (10421727..10423325)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (9977462..9979060)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene ryanodine receptor 3 Neighboring gene cytochrome c oxidase subunit 7C, mitochondrial-like Neighboring gene apoptosis and caspase activation inhibitor Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106999118 Neighboring gene ER membrane protein complex subunit 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of muscarinic receptor types in the primate ovary and evidence for nonneuronal acetylcholine synthesis. Fritz S, et al. J Clin Endocrinol Metab, 2001 Jan. PMID 11232023
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled acetylcholine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G protein-coupled serotonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gastric acid secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    muscarinic acetylcholine receptor M5
    Names
    muscarinic receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032931.1 → NP_001028103.1  muscarinic acetylcholine receptor M5

      See identical proteins and their annotated locations for NP_001028103.1

      Status: PROVISIONAL

      Source sequence(s)
      AF026264
      UniProtKB/Swiss-Prot
      P56490
      UniProtKB/TrEMBL
      G7MWA0
      Related
      ENSMMUP00000018686.2, ENSMMUT00000019965.4
      Conserved Domains (2) summary
      pfam00001
      Location:47 → 225
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:40 → 167
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      10421727..10423325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56490.1 GenPept UniProtKB/Swiss-Prot:P56490

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials