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    SF1 splicing factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717428, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SF1provided by VGNC
    Official Full Name
    splicing factor 1provided by VGNC
    Primary source
    VGNC:VGNC:77225
    See related
    Ensembl:ENSMMUG00000022606
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SF1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (9763965..9778273)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (9689817..9704206)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene menin 1 Neighboring gene mitogen-activated protein kinase kinase kinase kinase 2 Neighboring gene uncharacterized LOC106993199 Neighboring gene glycogen phosphorylase, muscle associated Neighboring gene RAS guanyl releasing protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      9763965..9778273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028833273.1 → XP_028689106.1  splicing factor 1 isoform X5

      Conserved Domains (2) summary
      smart00343
      Location:403 → 418
      ZnF_C2HC; zinc finger
      COG5176
      Location:142 → 382
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    2. XM_015113862.2 → XP_014969348.1  splicing factor 1 isoform X16

      UniProtKB/TrEMBL
      A0A1D5Q7H7
      Related
      ENSMMUP00000029764.3, ENSMMUT00000031813.4
      Conserved Domains (2) summary
      smart00343
      Location:278 → 293
      ZnF_C2HC; zinc finger
      COG5176
      Location:17 → 257
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    3. XM_015113857.2 → XP_014969343.1  splicing factor 1 isoform X10

      Conserved Domains (2) summary
      smart00343
      Location:278 → 293
      ZnF_C2HC; zinc finger
      COG5176
      Location:17 → 257
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    4. XM_015113853.2 → XP_014969339.1  splicing factor 1 isoform X7

      UniProtKB/TrEMBL
      A0A1D5Q7H7, F6SV41, H9EPF7
      Related
      ENSMMUP00000037470.3, ENSMMUT00000044453.3
      Conserved Domains (2) summary
      smart00343
      Location:278 → 293
      ZnF_C2HC; zinc finger
      COG5176
      Location:17 → 257
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    5. XM_015113858.2 → XP_014969344.1  splicing factor 1 isoform X12

      UniProtKB/TrEMBL
      F6Z712, G7NCH7, H9EPF6
      Conserved Domains (2) summary
      smart00343
      Location:278 → 293
      ZnF_C2HC; zinc finger
      COG5176
      Location:17 → 257
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    6. XM_015113856.2 → XP_014969342.1  splicing factor 1 isoform X9

      Conserved Domains (3) summary
      smart00343
      Location:278 → 293
      ZnF_C2HC; zinc finger
      cd02395
      Location:137 → 255
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16275
      Location:18 → 130
      SF1-HH; Splicing factor 1 helix-hairpin domain

    7. XM_028833278.1 → XP_028689111.1  splicing factor 1 isoform X11

      Conserved Domains (2) summary
      smart00343
      Location:278 → 293
      ZnF_C2HC; zinc finger
      COG5176
      Location:17 → 257
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    8. XM_015113861.2 → XP_014969347.1  splicing factor 1 isoform X14

      Conserved Domains (2) summary
      smart00343
      Location:163 → 178
      ZnF_C2HC; zinc finger
      cd02395
      Location:22 → 140
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...

    9. XM_028833279.1 → XP_028689112.1  splicing factor 1 isoform X15

      UniProtKB/TrEMBL
      G7NCH7
      Conserved Domains (2) summary
      smart00343
      Location:163 → 178
      ZnF_C2HC; zinc finger
      cd22382
      Location:20 → 112
      KH-I_SF1; type I K homology (KH) RNA-binding domain found in splicing factor 1 (SF1) and similar proteins

    10. XM_015113859.2 → XP_014969345.1  splicing factor 1 isoform X13

      UniProtKB/TrEMBL
      G7NCH7
      Conserved Domains (1) summary
      cl25681
      Location:17 → 257
      SF1-HH; Splicing factor 1 helix-hairpin domain

    11. XM_028833271.1 → XP_028689104.1  splicing factor 1 isoform X3

      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    12. XM_028833274.1 → XP_028689107.1  splicing factor 1 isoform X6

      Related
      ENSMMUP00000029763.4, ENSMMUT00000031812.4
      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    13. XM_028833269.1 → XP_028689102.1  splicing factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q7H7
      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    14. XM_028833272.1 → XP_028689105.1  splicing factor 1 isoform X4

      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    15. XM_028833270.1 → XP_028689103.1  splicing factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q7H7
      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    16. XM_028833276.1 → XP_028689109.1  splicing factor 1 isoform X8

      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

    17. XM_028833277.1 → XP_028689110.1  splicing factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q7H7
      Conserved Domains (2) summary
      smart00343
      Location:252 → 267
      ZnF_C2HC; zinc finger
      COG5176
      Location:10 → 231
      MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]
    Nucleotide Protein
    Heading Accession and Version

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